HAMAP annotation rule MF_01676
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Accession MF_01676
Dates 9-OCT-2008 (Created)
9-FEB-2012 (Last updated, Version 8)
Name AhpD
Scope Bacteria
Triggered by



Identifier
AHPD
Protein name
RecName: Full=Alkyl hydroperoxide reductase AhpD;
EC=1.11.1.15;
AltName: Full=Alkylhydroperoxidase AhpD;
Gene name
ahpD


FUNCTION Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity).
CATALYTIC ACTIVITY 2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH.
case <OC:Actinobacteria>
SUBUNIT Homotrimer (By similarity).
end case
SIMILARITY Belongs to the AhpD family.


Antioxidant
case <FT:3> or <FT:4>
Disulfide bond
end case
Oxidoreductase
Peroxidase
Redox-active center


GO:0008785; Molecular function: alkyl hydroperoxide reductase activity.
GO:0016209; Molecular function: antioxidant activity.


Pfam PF02627; CMD; 1;
TIGRFAMs TIGR00777; AhpD; 1;
TIGR00778; AhpD_dom; 1;


From: AHPD_MYCTU (P0A5N4)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     130     130       Proton donor (By similarity)     C  
ACT_SITE     133     133       Cysteine sulfenic acid (-SOH) intermediate (By similarity)     C  
DISULFID     130     133       Alternate (By similarity)     C-x*-C  
DISULFID     133     133       Interchain (with AhpC); in linked form (By similarity)     C  


Size range: 173-194 amino acids
Related Rules: None
Template: P0A5N4 (AHPD_MYCTU)
Fusion: None


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