HAMAP

Accession	MF_01676
Dates	9-OCT-2008 (Created) 31-MAR-2010 (Last updated, Version 7)

Data class

Protein

Predictors

HAMAP; MF_01676; [distribution of match scores in UniProtKB];[seed alignment for MF_01676]

Names

AhpD

Identifier

AHPD

Protein name

RecName: Full=Alkyl hydroperoxide reductase AhpD; EC=1.11.1.15; AltName: Full=Alkylhydroperoxidase AhpD;

Gene name

ahpD

FUNCTION: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity).

CATALYTIC ACTIVITY: 2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH.

SUBUNIT: Homotrimer (By similarity).

SIMILARITY: Belongs to the AhpD family.

Pfam	PF02627; CMD; 1;
TIGRFAMs	TIGR00777; ahpD; 1; TIGR00778; ahpD_dom; 1;

Antioxidant.

Disulfide bond.

Oxidoreductase, Peroxidase, Redox-active center.

GO:0008785; Molecular function: alkyl hydroperoxide reductase activity.
GO:0016209; Molecular function: antioxidant activity.

From: AHPD_MYCTU (P0A5N4)
Key		From		To		Description		Condition		FTGroup
ACT_SITE		130		130		Proton donor (By similarity)		C
ACT_SITE		133		133		Cysteine sulfenic acid (-SOH) intermediate (By similarity)		C
DISULFID		130		133		Alternate (By similarity)		C-x*-C
DISULFID		133		133		Interchain (with AhpC); in linked form (By similarity)		C

Size range:	173-194 amino acids
Related UniRules:	None
Template:	P0A5N4 (AHPD_MYCTU)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None