HAMAP

Accession	MF_01677
Dates	15-OCT-2008 (Created) 11-OCT-2010 (Last updated, Version 13)

Data class

Protein

Predictors

HAMAP; MF_01677; [distribution of match scores in UniProtKB];[seed alignment for MF_01677]

Names

Salvage_MtnB

Identifier

MTNB

Protein name

RecName: Full=Methylthioribulose-1-phosphate dehydratase; Short=MTRu-1-P dehydratase; EC=4.2.1.109;

Gene name

mtnB

FUNCTION: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) (By similarity).

CATALYTIC ACTIVITY: S-methyl-5-thio-D-ribulose 1-phosphate = 5-(methylthio)-2,3-dioxopentyl phosphate + H(2)O.

COFACTOR: Binds 1 zinc ion per subunit (By similarity).

PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.

SUBUNIT: Homotetramer (By similarity).

SIMILARITY: Belongs to the aldolase class II family. MtnB subfamily.

Pfam	PF00596; Aldolase_II; 1;
TIGRFAMs	TIGR03328; salvage_mtnB; 1;

Amino-acid biosynthesis, Lyase, Metal-binding, Methionine biosynthesis, Zinc.

GO:0008270; Molecular function: zinc ion binding.
GO:0046570; Molecular function: methylthioribulose 1-phosphate dehydratase activity.
GO:0019284; Biological process: L-methionine biosynthetic process from S-adenosylmethionine.

From: MTNB_BACSU (O31668)
Key		From		To		Description		Condition		FTGroup
METAL		98		98		Zinc (By similarity)		H
METAL		100		100		Zinc (By similarity)		H

Size range:	194-250 amino acids
Related UniRules:	None
Template:	O31668 (MTNB_BACSU)
Scope:	Bacteria
Fusion:	Nter: MF_01680 (mtnX); Cter: None
Duplicate:	in XANOP
Plasmid encoded:	None