HAMAP

Accession	MF_01689
Dates	1-APR-2009 (Created) 29-MAR-2010 (Last updated, Version 7)

Data class

Protein

Predictors

HAMAP; MF_01689; [distribution of match scores in UniProtKB];[seed alignment for MF_01689]

Names

Ornith_aminotrans_3

Identifier

OAT

Protein name

RecName: Full=Ornithine aminotransferase; Short=OAT; EC=2.6.1.13; AltName: Full=Ornithine--oxo-acid aminotransferase;

Gene name

rocD

FUNCTION: Catalyzes the interconversion of ornithine to glutamate semialdehyde (By similarity).

CATALYTIC ACTIVITY: L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.

COFACTOR: Pyridoxal phosphate (By similarity).

PATHWAY: Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1.

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.

PROSITE	PS00600; AA_TRANSFER_CLASS_3; 1;
Pfam	PF00202; Aminotran_3; 1;
TIGRFAMs	TIGR01885; Orn_aminotrans; 1;

Amino-acid biosynthesis, Aminotransferase, Cytoplasm, Proline biosynthesis, Pyridoxal phosphate, Transferase.

GO:0004587; Molecular function: ornithine-oxo-acid transaminase activity.
GO:0008483; Molecular function: transaminase activity.
GO:0030170; Molecular function: pyridoxal phosphate binding.
GO:0006561; Biological process: proline biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

From: OAT_BACSU (P38021)
Key		From		To		Description		Condition		FTGroup
MOD_RES		258		258		N6-(pyridoxal phosphate)lysine (By similarity)		K

Size range:	394-411 amino acids
Related UniRules:	MF_01107 (ARGD)
Template:	P38021 (OAT_BACSU)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in STAAC, STAAM, STAAN, STAAR, STAAS, STAAW, STAS1
Plasmid encoded:	None