HAMAP rule MF_01692
General rule information
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| Accession | MF_01692 |
| Dates | 30-APR-2009 (Created)
1-JUN-2023 (Last updated, Version 13) |
| Name | DapEL |
| Scope(s) |
Bacteria Bacillota |
| Template(s) | O34916 (DAPEL_BACSU); D5E0A1 (DAPEL_PRIM1); [ Recover all ] |
| Triggered by |
HAMAP; MF_01692 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | DAPEL |
| Protein name | RecName: Full=N-acetyldiaminopimelate deacetylase; EC=3.5.1.47; |
Comments
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| FUNCTION | Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate. |
| CATALYTIC ACTIVITY | Reaction=H2O + N-acetyl-(2S,6S)-2,6-diaminoheptanedioate = (2S,6S)-2,6- diaminoheptanedioate + acetate; Xref=Rhea:RHEA:20405, ChEBI:CHEBI:15377, ChEBI:CHEBI:30089, ChEBI:CHEBI:57609, ChEBI:CHEBI:58767; EC=3.5.1.47; |
| PATHWAY | Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (acetylase route): step 3/3. |
| SIMILARITY | Belongs to the peptidase M20A family. N- acetyldiaminopimelate deacetylase subfamily. |
Keywords
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Gene Ontology
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| GO:0050118; Molecular function:N-acetyldiaminopimelate deacetylase activity |
| GO:0009089; Biological process:lysine biosynthetic process via diaminopimelate |
| GO:0019877; Biological process:diaminopimelate biosynthetic process |
Cross-references
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| PROSITE | PS00758; ARGE_DAPE_CPG2_1; 1; |
| PROSITE | PS00759; ARGE_DAPE_CPG2_2; 1; |
| Pfam | PF07687; M20_dimer; 1; |
| Pfam | PF01546; Peptidase_M20; 1; |
| NCBIfam | TIGR01891; Amidohydrolases; 1; |
Features
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| From: DAPEL_BACSU (O34916) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 69 | 69 | D | |||||||||
| ACT_SITE | 128 | 128 | /note="Proton acceptor" | E | ||||||||
Additional information
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| Size range | 370-414 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | DapL is not used as gene name, because it is already used for LL-diaminopimelate aminotransferase |