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HAMAP annotation rule: MF_01701
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General rule information

Accession MF_01701
Dates 11-OCT-2004 (Created)
28-SEP-2010 (Last updated, Version 16)
Data class Protein
Predictors PROSITE; PS51237; [distribution of match scores in UniProtKB]
Names ABC_ATPase_CysA


Propagated annotation

Identifier, protein and gene names
Identifier CYSA
Protein name
RecName: Full=Sulfate/thiosulfate import ATP-binding protein CysA;
EC=3.6.3.25;
AltName: Full=Sulfate-transporting ATPase;
Gene name cysA
Comments

case <OC:Bacteria>
FUNCTION: Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system (By similarity).
CATALYTIC ACTIVITY: ATP + H(2)O + sulfate(Out) = ADP + phosphate + sulfate(In).
SUBUNIT: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP) (Potential).
SIMILARITY: Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
end case


case <OC:Bacteria> and (not defined <Property:Membrane> or <Property:Membrane=1>)
SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein (By similarity).

else case <OC:Bacteria> and <Property:Membrane=2>
SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane protein (By similarity).
end case


case <OG:Chloroplast>
FUNCTION: Part of the ABC transporter complex involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system (By similarity).
CATALYTIC ACTIVITY: ATP + H(2)O + sulfate(Out) = ADP + phosphate + sulfate(In).
SUBCELLULAR LOCATION: Plastid, chloroplast (Potential).
SIMILARITY: Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
end case

Cross-references
Pfam PF00005; ABC_tran; 1;
PF03459; TOBE; 1;
TIGRFAMs TIGR00968; 3a0106s01; 1;
PROSITE PS00211; ABC_TRANSPORTER_1; 1;
PS50893; ABC_TRANSPORTER_2; 1; trigger=PRU00434;
Gene Ontology
GO:0008272; Biological process: sulfate transport.
GO:0015419; Molecular function: sulfate transmembrane-transporting ATPase activity.

case <OC:Bacteria>
GO:0005886; Cellular component: plasma membrane.
end case


case <OG:Chloroplast>
GO:0009507; Cellular component: chloroplast.
end case

Keywords
Transport, Sulfate transport, Hydrolase.

case <OG:Chloroplast>
Chloroplast, Plastid.
end case



Additional information

Size range: 236-406 amino acids
Related UniRules: PRU01700
Template: P16676 (CYSA_ECOLI)
Scope: Bacteria; Actinobacteria
Bacteria; Cyanobacteria
Bacteria; Firmicutes
Bacteria; Proteobacteria
Bacteria; Spirochaetes
Plastid
Fusion: Nter: None; Cter: None
Duplicate: in AGRT5, BACCR, RHIME, SHEON, VIBCH, VIBVU, YERPE
Plasmid encoded: in RHIME

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UniProtKB rule member sequences