HAMAP

Accession	MF_01703
Dates	11-OCT-2004 (Created) 5-OCT-2010 (Last updated, Version 14)

Data class

Protein

Predictors

PROSITE; PS51239; [distribution of match scores in UniProtKB]

Names

ABC_ATPase_TM_MsbA

Identifier

MSBA

Protein name

RecName: Full=Lipid A export ATP-binding/permease protein MsbA; EC=3.6.3.-;

Gene name

msbA

FUNCTION: Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity).

SUBUNIT: Homodimer (By similarity).

DOMAIN: In MsbA the ATP-binding domain (NBD) and the transmembrane domain (TMD) are fused.

SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (Potential).

SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein (Potential).

SIMILARITY: Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.

Pfam	PF00005; ABC_tran; 1;
TIGRFAMs	TIGR02203; MsbA_lipidA; 1;
PROSITE	PS50929; ABC_TM1F; 1; trigger=PRU00441; PS00211; ABC_TRANSPORTER_1; 1; PS50893; ABC_TRANSPORTER_2; 1; trigger=PRU00434;
General	Transmembrane; -; 5-6;

GO:0006869; Biological process: lipid transport.
GO:0005319; Molecular function: lipid transporter activity.

GO:0005886; Cellular component: plasma membrane.

Transport, Lipid transport, Hydrolase, Membrane, Cell membrane, Transmembrane, Transmembrane helix.

Size range:	572-675 amino acids
Related UniRules:	PRU01700
Template:	P60752 (MSBA_ECOLI)
Scope:	Bacteria; Proteobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None