Annotation rule MF_01707
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General rule information [?]

Accession MF_01707
Dates 11-OCT-2004 (Created)
15-AUG-2012 (Last updated, Version 17)
Name ABC_ATPase_CcmA
Scope Bacteria; Deinococci
Bacteria; Proteobacteria
Eukaryota; Arabidopsis
Mitochondrion
Triggered by PROSITE; PS51243

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
CCMA
Protein name
RecName: Full=Cytochrome c biogenesis ATP-binding export protein CcmA;
EC=3.6.3.41;
AltName: Full=Heme exporter protein A;
Gene name
ccmA

Comments [?]

case <OC:Bacteria> or <OG:Mitochondrion>
Function Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity).
Catalytic activity ATP + H(2)O + heme(In) = ADP + phosphate + heme(Out).
Subunit The complex is composed of two ATP-binding proteins (CcmA) and two transmembrane proteins (CcmB) (By similarity).
Similarity Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
end case
case <OC:Bacteria> and (not defined <Property:Membrane> or <Property:Membrane=1>)
Subcellular location Cell membrane; Peripheral membrane protein (By similarity).
end case
case <OC:Bacteria> and (defined <Property:Membrane> and <Property:Membrane=2>)
Subcellular location Cell inner membrane; Peripheral membrane protein (By similarity).
end case
case <OG:Mitochondrion>
Subcellular location Mitochondrion membrane; Peripheral membrane protein (By similarity).
end case

Keywords [?]

case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=2>
end case
case <OC:Bacteria>
end case

Gene Ontology [?]

GO:0006810; Biological process: transport.
GO:0005215; Molecular function: transporter activity.
case <OC:Bacteria>
GO:0005886; Cellular component: plasma membrane.
end case
case <OG:Mitochondrion>
GO:0031966; Cellular component: mitochondrial membrane.
end case

Cross-references [?]

Pfam PF00005; ABC_tran; 1;
TIGRFAMs TIGR01189; CcmA; 1;
PROSITE PS00211; ABC_TRANSPORTER_1; 1;
PS50893; ABC_TRANSPORTER_2; 1; trigger=PRU00434;

Additional information [?]

Size range 192-345 amino acids
Related rules PRU01700
Template P33931 (CCMA_ECOLI)
Fusion Nter: None; Cter: ccmE