HAMAP rule MF_01713
General rule information
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| Accession | MF_01713 |
| Dates | 28-JAN-2005 (Created)
1-JUN-2023 (Last updated, Version 23) |
| Name | ABC_ATPase_PhnC |
| Scope(s) |
Bacteria Archaea |
| Template(s) | P16677 (PHNC_ECOLI); [ Recover all ] |
| Triggered by |
PROSITE; PS51249 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | PHNC |
| Protein name | RecName: Full=Phosphonates import ATP-binding protein PhnC; EC=7.3.2.2; |
| Gene name | Name=phnC; |
Comments
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| FUNCTION | Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system. |
| CATALYTIC ACTIVITY | Reaction=ATP + H2O + phosphonate(out) = ADP + H(+) + phosphate + phosphonate(in); Xref=Rhea:RHEA:18065, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16215, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.3.2.2; |
| SUBUNIT | The complex is composed of two ATP-binding proteins (PhnC), two transmembrane proteins (PhnE) and a solute-binding protein (PhnD). |
| case not defined <Property:Membrane> or <Property:Membrane=1> | |
| SUBCELLULAR LOCATION | Cell membrane; Peripheral membrane protein. |
| else case <Property:Membrane=2> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Peripheral membrane protein. |
| end case | |
| SIMILARITY | Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family. |
Keywords
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| ATP-binding | |
| case defined <Property:Membrane> and <Property:Membrane=2> | |
| Cell inner membrane | |
| end case | |
| Cell membrane | |
| Membrane | |
| Nucleotide-binding | |
| Transport | |
| <a href="https://www.uniprot.org/keywords/KW-1278">Translocase</a> | |
| Phosphonate transport | |
Gene Ontology
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| GO:0015716; Biological process:organic phosphonate transport |
| GO:0015416; Molecular function:ABC-type phosphonate transporter activity |
| GO:0005886; Cellular component:plasma membrane |
Cross-references
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| Pfam | PF00005; ABC_tran; 1; |
| NCBIfam | TIGR02315; ABC_phnC; 1; |
| PROSITE | PS00211; ABC_TRANSPORTER_1; 1; |
| PROSITE | PS50893; ABC_TRANSPORTER_2; 1; |
Features
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Additional information
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| Size range | 240-280 amino acids |
| Related rules |
PRU01700 |
| Fusion | Nter: None Cter: None |
| Comments | In STUST two additionnal operons might be present, with a narrow specificity than phophonate transport the first one ptxABC for phosphite transport and htxBCDE for hypophophite transport. Both ABC ATPase are match by the phnC profile due two a high sequence similarity. |