HAMAP rule MF_01723

General rule information [?]

Accession	MF_01723
Dates	8-JAN-2007 (Created) 1-JUN-2023 (Last updated, Version 24)
Name	ABC_ATPase_ThiQ
Scope(s)	Bacteria Pseudomonadota
Template(s)	P31548 (THIQ_ECOLI); P44986 (THIQ_HAEIN); [ Recover all ]
Triggered by	PROSITE; PS51288 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	THIQ
Protein name	RecName: Full=Thiamine import ATP-binding protein ThiQ; EC=7.6.2.15;
Gene name	Name=thiQ;

Comments [?]

FUNCTION	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system.
CATALYTIC ACTIVITY	Reaction=ATP + H2O + thiamine(out) = ADP + H(+) + phosphate + thiamine(in); Xref=Rhea:RHEA:29811, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:18385, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.6.2.15;
SUBUNIT	The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB).
SIMILARITY	Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.
case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATION	Cell membrane; Peripheral membrane protein.
else case <Property:Membrane=2>
SUBCELLULAR LOCATION	Cell inner membrane; Peripheral membrane protein.
end case

Keywords [?]

ATP-binding
case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
Cell membrane
Membrane
Nucleotide-binding
Transport
<a href="https://www.uniprot.org/keywords/KW-1278">Translocase</a>

Gene Ontology [?]

GO:0015888; Biological process:thiamine transport

GO:0048502; Molecular function:ABC-type thiamine transporter activity

GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Features [?]

Additional information [?]