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HAMAP rule MF_01726

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General rule information [?]

Accession MF_01726
Dates 3-APR-2007 (Created)
1-JUN-2023 (Last updated, Version 26)
Name ABC_ATPase_PotA
Scope(s) Bacteria
Template(s) P69874 (POTA_ECOLI); [ Recover all ]
Triggered by PROSITE; PS51305 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier POTA
Protein name RecName: Full=Spermidine/putrescine import ATP-binding protein PotA;
                 EC=7.6.2.11;
Gene name Name=potA;

Comments [?]

FUNCTIONPart of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
CATALYTIC ACTIVITY Reaction=ATP + H2O + polyamine-[polyamine-binding protein]Side 1 = ADP + phosphate + polyamineSide 2 + [polyamine-binding protein]Side 1.; EC=7.6.2.11;
SUBUNITThe complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).
case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATIONCell membrane; Peripheral membrane protein.
else case <Property:Membrane=2>
SUBCELLULAR LOCATIONCell inner membrane; Peripheral membrane protein.
end case
SIMILARITYBelongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.

Keywords [?]

ATP-binding
case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
Cell membrane
Membrane
Nucleotide-binding
Transport
<a href="https://www.uniprot.org/keywords/KW-1278">Translocase</a>

Gene Ontology [?]

GO:0015846; Biological process:polyamine transport
GO:0015417; Molecular function:ABC-type polyamine transporter activity
GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam PF00005; ABC_tran; 1;
NCBIfam TIGR01187; PotA; 1;
PROSITE PS00211; ABC_TRANSPORTER_1; 1;
PROSITE PS50893; ABC_TRANSPORTER_2; 1;

Features [?]


Additional information [?]

Size range 250-300 amino acids
Related rules PRU01700
Fusion Nter: None Cter: None



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