HAMAP

Accession	MF_01803
Dates	9-JAN-2004 (Created) 2-DEC-2011 (Last updated, Version 20)

Data class

Protein

Predictors

HAMAP; MF_01803; [distribution of match scores in UniProtKB];[seed alignment for MF_01803]

Names

MukF

Identifier

MUKF

Protein name

RecName: Full=Chromosome partition protein mukF;

Gene name

mukF

FUNCTION: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with mukB and mukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity).

SUBUNIT: Interacts, and probably forms a ternary complex, with mukE and mukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between mukE and mukB (By similarity).

SUBCELLULAR LOCATION: Cytoplasm, nucleoid (By similarity). Note=Restricted to the nucleoid region (By similarity).

SIMILARITY: Belongs to the mukF family.

Pfam	PF03882; KicB; 1;

Cytoplasm, Cell cycle, Cell division, Chromosome partition, DNA condensation, Calcium.

GO:0005737; Cellular component: cytoplasm.
GO:0006260; Biological process: DNA replication.
GO:0007059; Biological process: chromosome segregation.
GO:0005509; Molecular function: calcium ion binding.

From: MUKF_ECOLI (P60293)
Key		From		To		Description		Condition		FTGroup
DOMAIN		208		236		Leucine-zipper		L-x(6)-L-x(6)-L-x(6)-L-x(6)-[LI]

Size range:	440-445 amino acids
Related UniRules:	None
Template:	P60293 (MUKF_ECOLI)
Scope:	Bacteria; Gammaproteobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None