HAMAP rule MF_01803
General rule information
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| Accession | MF_01803 |
| Dates | 9-JAN-2004 (Created)
19-NOV-2019 (Last updated, Version 24) |
| Name | MukF |
| Scope(s) |
Bacteria Gammaproteobacteria |
| Template(s) | P60293 (MUKF_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_01803 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | MUKF |
| Protein name | RecName: Full=Chromosome partition protein MukF; |
| Gene name | Name=mukF; |
Comments
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| FUNCTION | Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity. |
| SUBUNIT | Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB. |
| SUBCELLULAR LOCATION | Cytoplasm, nucleoid. Note=Restricted to the nucleoid region. |
| SIMILARITY | Belongs to the MukF family. |
Keywords
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Gene Ontology
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| GO:0005737; Cellular component:cytoplasm |
| GO:0006260; Biological process:DNA replication |
| GO:0007059; Biological process:chromosome segregation |
| GO:0005509; Molecular function:calcium ion binding |
Cross-references
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| Pfam | PF03882; KicB; 1; |
Features
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| From: MUKF_ECOLI (P60293) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| REGION | 208 | 236 | /note="Leucine-zipper" | L-x(6)-L-x(6)-L-x(6)-L-x(6)-[LI] | ||||||||
Additional information
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| Size range | 440-445 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |