HAMAP

Accession	MF_01805
Dates	17-DEC-2003 (Created) 14-APR-2011 (Last updated, Version 13)

Data class

Protein

Predictors

HAMAP; MF_01805; [distribution of match scores in UniProtKB];[seed alignment for MF_01805]

Names

ScpA

Identifier

SCPA

Protein name

RecName: Full=Segregation and condensation protein A;

Gene name

scpA

FUNCTION: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity).

SUBUNIT: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity). Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells (By similarity).

SIMILARITY: Belongs to the ScpA family.

Pfam	PF02616; ScpA_ScpB; 1;

Cytoplasm, Cell cycle, Cell division, Chromosome partition.

GO:0006260; Biological process: DNA replication.
GO:0007059; Biological process: chromosome segregation.
GO:0005737; Cellular component: cytoplasm.

Size range:	233-300 amino acids
Related UniRules:	None
Template:	P35154 (SCPA_BACSU)
Scope:	Bacteria; Firmicutes
Fusion:	Nter: <dihydrofolate reductase-like>; Cter: None
Duplicate:	None
Plasmid encoded:	None
Comments:	In MYCGA, MYCGE and MYCPN the protein is fused in its N-terminus with a domain that is strongly related to the dihydrofolate reductase domain.