HAMAP

Accession	MF_01820
Dates	30-OCT-2003 (Created) 29-SEP-2011 (Last updated, Version 21)

Data class

Protein

Predictors

HAMAP; MF_01820; [distribution of match scores in UniProtKB];[seed alignment for MF_01820]

Names

GTPase_RsgA

Identifier

RSGA

Protein name

RecName: Full=Putative ribosome biogenesis GTPase RsgA; EC=3.6.1.-;

Gene name

rsgA

FUNCTION: May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity).

COFACTOR: Binds 1 zinc ion per subunit (By similarity).

SUBUNIT: Monomer (By similarity). Associates with ribosomes (By similarity).

SIMILARITY: Belongs to the RsgA GTPase family.

Pfam	PF03193; DUF258; 1;
TIGRFAMs	TIGR00157; TIGR00157; 1;
PROSITE	PS50936; ENGC_GTPASE; 1; trigger=PRU00287;

Hydrolase, GTP-binding, Nucleotide-binding.

Zinc, Metal-binding.

GO:0003924; Molecular function: GTPase activity.
GO:0005525; Molecular function: GTP binding.

From: RSGA_SALTY (Q8ZKB0)
Key		From		To		Description		Condition		FTGroup
NP_BIND		160		163		GTP (By similarity)		[NTSA]-K-x-D
NP_BIND		214		222		GTP (By similarity)		[AG]-x(4)-G-K-[ST]-[TS]

Key		From		To		Description		Condition		FTGroup
MOTIF		297		310		Knuckle-like cysteine cluster

Key		From		To		Description		Condition		FTGroup
METAL		297		297		Zinc (By similarity)		C		1
METAL		302		302		Zinc (By similarity)		C		1
METAL		304		304		Zinc (By similarity)		H		1
METAL		310		310		Zinc (By similarity)		C		1

Size range:	272-387 amino acids
Related UniRules:	None
Template:	P39286 (RSGA_ECOLI); Q9X242 (RSGA_THEMA): [Recover all]
Scope:	Bacteria Archaea; Methanosarcinales
Fusion:	Nter: None; Cter: None
Duplicate:	in NOSS1, BACTN, LACPL, LISIN, LISMO, OCEIH, VIBPA, VIBVU
Plasmid encoded:	in NOSS1
Comments:	In contrast to most P-loop GTPases, which have a G1-G2-G3-G4 pattern of GTP-binding motifs, contains a permuted G4-G1-G2-G3 pattern. Often referred to as YjeQ.