HAMAP rule MF_01841
General rule information
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Accession | MF_01841 |
Dates | 28-JUL-2005 (Created)
7-MAY-2024 (Last updated, Version 23) |
Name | Agmatine_deimin |
Scope(s) |
Bacteria |
Template(s) | Q9I6J9 (AGUA_PSEAE); [ Recover all ] |
Triggered by |
HAMAP; MF_01841 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | AGUA |
case <OC:Pseudomonadales> | |
Protein name | RecName: Full=Agmatine deiminase; EC=3.5.3.12; AltName: Full=Agmatine iminohydrolase; |
end case | |
case not <OC:Pseudomonadales> | |
Protein name | RecName: Full=Putative agmatine deiminase; EC=3.5.3.12; AltName: Full=Agmatine iminohydrolase; |
end case | |
Gene name | Name=aguA; |
Comments
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case <OC:Pseudomonadales> | |
FUNCTION | Mediates the hydrolysis of agmatine into N- carbamoylputrescine in the arginine decarboxylase (ADC) pathway of putrescine biosynthesis, a basic polyamine. |
CATALYTIC ACTIVITY | Reaction=agmatine + H2O = N-carbamoylputrescine + NH4(+); Xref=Rhea:RHEA:18037, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:58145, ChEBI:CHEBI:58318; EC=3.5.3.12; |
PATHWAY | Amine and polyamine biosynthesis; putrescine biosynthesis via agmatine pathway; N-carbamoylputrescine from agmatine: step 1/1. |
SUBUNIT | Homodimer. |
end case | |
case not <OC:Pseudomonadales> | |
CATALYTIC ACTIVITY | Reaction=agmatine + H2O = N-carbamoylputrescine + NH4(+); Xref=Rhea:RHEA:18037, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:58145, ChEBI:CHEBI:58318; EC=3.5.3.12; |
end case | |
SIMILARITY | Belongs to the agmatine deiminase family. |
Keywords
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Hydrolase | |
case <OC:Pseudomonadales> | |
Polyamine biosynthesis | |
end case |
Gene Ontology
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GO:0047632; Molecular function:agmatine deiminase activity | |
case <OCellular component:Pseudomonadales> | |
GO:0033388; Biological process:putrescine biosynthetic process from arginine | |
end case |
Cross-references
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Pfam | PF04371; PAD_porph; 1; |
Features
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From: AGUA_PSEAE (Q9I6J9) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
ACT_SITE | 357 | 357 | /note="Amidino-cysteine intermediate" | C |
Additional information
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Size range | 339-371 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |