HAMAP

Accession	MF_01853
Dates	18-DEC-2008 (Created) 29-SEP-2011 (Last updated, Version 4)

Data class

Protein

Predictors

HAMAP; MF_01853; [distribution of match scores in UniProtKB];[seed alignment for MF_01853]

Names

PelO

Identifier

PELO

Protein name

RecName: Full=Protein pelota homolog; EC=3.1.-.-;

Gene name

pelA

FUNCTION: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity (By similarity).

COFACTOR: Divalent metal cations (By similarity).

SUBUNIT: Monomer (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (Potential).

DOMAIN: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity (By similarity).

SIMILARITY: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.

Pfam	PF03463; eRF1_1; 1; PF03464; eRF1_2; 1; PF03465; eRF1_3; 1;
TIGRFAMs	TIGR00111; Pelota; 1;

Cytoplasm, Endonuclease, Hydrolase, Metal-binding, Nuclease.

GO:0004519; Molecular function: endonuclease activity.
GO:0046872; Molecular function: metal ion binding.
GO:0005737; Cellular component: cytoplasm.

Size range:	328-360 amino acids
Related UniRules:	None
Template:	Q9HJ74 (PELO_THEAC); P96026 (PELO_SULSO): [Recover all]
Scope:	Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None