HAMAP

Accession	MF_01865
Dates	15-APR-2009 (Created) 29-SEP-2011 (Last updated, Version 9)

Data class

Protein

Predictors

HAMAP; MF_01865; [distribution of match scores in UniProtKB];[seed alignment for MF_01865]

Names

MTTase_RimO

Identifier

RIMO

Protein name

RecName: Full=Ribosomal protein S12 methylthiotransferase RimO; Short=S12 MTTase; Short=S12 methylthiotransferase; EC=2.-.-.-; AltName: Full=Ribosome maturation factor RimO;

Gene name

rimO

FUNCTION: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity).

COFACTOR: Binds 2 4Fe-4S clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (Potential).

SIMILARITY: Belongs to the methylthiotransferase family. RimO subfamily.

PROSITE	PS50926; TRAM; 0-1; trigger=PRU00208; PS01278; MTTASE_RADICAL; 1; PS51449; MTTASE_N; 1; trigger=PRU00780;
Pfam	PF04055; Radical_SAM; 1; PF01938; TRAM; 0-1; PF00919; UPF0004; 1;
TIGRFAMs	TIGR01125; TIGR01125; 1; TIGR00089; TIGR00089; 1;

4Fe-4S, Cytoplasm, Iron, Iron-sulfur, Metal-binding, S-adenosyl-L-methionine, Transferase.

GO:0016740; Molecular function: transferase activity.
GO:0051539; Molecular function: 4 iron, 4 sulfur cluster binding.
GO:0018339; Biological process: peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid.
GO:0005737; Cellular component: cytoplasm.

From: RIMO_ECOLI (P0AEI4)
Key		From		To		Description		Condition		FTGroup
METAL		17		17		Iron-sulfur (4Fe-4S) (By similarity)		C		1
METAL		53		53		Iron-sulfur (4Fe-4S) (By similarity)		C		1
METAL		82		82		Iron-sulfur (4Fe-4S) (By similarity)		C		1
METAL		150		150		Iron-sulfur (4Fe-4S-S-AdoMet) (By similarity)		C		2
METAL		154		154		Iron-sulfur (4Fe-4S-S-AdoMet) (By similarity)		C		2
METAL		157		157		Iron-sulfur (4Fe-4S-S-AdoMet) (By similarity)		C		2

Size range:	401-545 amino acids
Related UniRules:	None
Template:	P0AEI4 (RIMO_ECOLI)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None