HAMAP rule MF_01938

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_01938
Accession	MF_01938
Dates	28-OCT-2014 (Created) 10-OCT-2024 (Last updated, Version 9)
Name	MenA_2
Scope(s)	Bacteria Cyanobacteriota
Template(s)	P73962 (MENA_SYNY3); [ Recover all ]
Triggered by	HAMAP; MF_01938 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	MENA
Protein name	RecName: Full=2-carboxy-1,4-naphthoquinone phytyltransferase; EC=2.5.1.130; AltName: Full=1,4-dihydroxy-2-naphthoate phytyltransferase; Short=DHNA phytyltransferase;
Gene name	Name=menA;

Comments [?]

FUNCTION	Involved in the synthesis of phylloquinone (vitamin K1). Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4- naphthoquinone.
CATALYTIC ACTIVITY	Reaction=2-carboxy-1,4-naphthoquinone + phytyl diphosphate + H(+) = demethylphylloquinone + CO2 + diphosphate; Xref=Rhea:RHEA:47740, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:31087, ChEBI:CHEBI:33019, ChEBI:CHEBI:75434, ChEBI:CHEBI:87842; EC=2.5.1.130;
PATHWAY	Cofactor biosynthesis; phylloquinone biosynthesis.
SUBCELLULAR LOCATION	Cell inner membrane; Multi-pass membrane protein.
SIMILARITY	Belongs to the MenA family. Type 2 subfamily.

Keywords [?]

Gene Ontology [?]

GO:0016765; Molecular function:transferase activity, transferring alkyl or aryl (other than methyl) groups

GO:0042372; Biological process:phylloquinone biosynthetic process

GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Features [?]

Additional information [?]