HAMAP rule MF_01954
General rule information
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| Accession | MF_01954 |
| Dates | 10-APR-2006 (Created)
7-MAY-2024 (Last updated, Version 23) |
| Name | Urease_beta |
| Scope(s) |
Bacteria Archaea Halobacteria |
| Template(s) | P41021 (URE2_SPOPA); P18315 (URE2_KLEAE); [ Recover all ] |
| Triggered by |
HAMAP; MF_01954 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | URE2 |
| Protein name | RecName: Full=Urease subunit beta; EC=3.5.1.5; AltName: Full=Urea amidohydrolase subunit beta; |
| Gene name | Name=ureB; |
Comments
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| CATALYTIC ACTIVITY | Reaction=2 H(+) + H2O + urea = CO2 + 2 NH4(+); Xref=Rhea:RHEA:20557, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16199, ChEBI:CHEBI:16526, ChEBI:CHEBI:28938; EC=3.5.1.5; |
| PATHWAY | Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1. |
| SUBUNIT | Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the urease beta subunit family. |
Keywords
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Gene Ontology
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| GO:0009039; Molecular function:urease activity |
| GO:0043419; Biological process:urea catabolic process |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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Features
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Additional information
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| Size range | 101-164 amino acids |
| Related rules |
MF_01955 |
| Fusion | Nter: None Cter: None |
| Comments | Fused with the urease gamma subunit in a number of bacterial species and in SULTO |