HAMAP rule MF_01958
General rule information
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| Accession | MF_01958 |
| Dates | 22-MAY-2006 (Created)
19-NOV-2019 (Last updated, Version 14) |
| Name | Acetyl_esterase |
| Scope(s) |
Bacteria Enterobacterales |
| Template(s) | P23872 (AES_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_01958 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | AES |
| Protein name | RecName: Full=Acetyl esterase; EC=3.1.1.-; |
| Gene name | Name=aes; |
Comments
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| FUNCTION | Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity. |
| SUBUNIT | Homodimer. Interacts with MalT and MelA. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the 'GDXG' lipolytic enzyme family. |
Keywords
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Gene Ontology
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| GO:0052689; Molecular function:carboxylic ester hydrolase activity |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| PROSITE | PS01173; LIPASE_GDXG_HIS; 1; |
| PROSITE | PS01174; LIPASE_GDXG_SER; 1; |
| Pfam | PF07859; Abhydrolase_3; 1; |
Features
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| From: AES_ECOLI (P23872) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 165 | 165 | S | |||||||||
| ACT_SITE | 262 | 262 | D | |||||||||
| ACT_SITE | 292 | 292 | H | |||||||||
Additional information
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| Size range | 272-323 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |