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| HAMAP annotation rule MF_01961 |
| Accession |
MF_01961 |
| Dates |
23-OCT-2008 (Created)
9-NOV-2012 (Last updated, Version 13) |
| Scope |
Bacteria
Archaea; Euryarchaeota |
case <OC:Bacteria> or <OC:Archaea>
end case
| Protein name |
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RecName:
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Full=Catalase-peroxidase;
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Short=CP;
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EC=1.11.1.21;
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AltName:
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Full=Peroxidase/catalase;
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| FUNCTION |
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity (By similarity). |
| CATALYTIC ACTIVITY |
Donor + H(2)O(2) = oxidized donor + 2 H(2)O. |
|
2 H(2)O(2) = O(2) + 2 H(2)O. |
| COFACTOR |
Binds 1 heme B (iron-protoporphyrin IX) group per dimer (By similarity). |
| SUBUNIT |
Homodimer or homotetramer (By similarity). |
| PTM |
The covalent Trp-Tyr-Met adduct is important for the catalase, but not the peroxidase activity of the enzyme (By similarity). |
| SIMILARITY |
Belongs to the peroxidase family. Peroxidase/catalase subfamily. |
GO:0004096; Molecular function: catalase activity.
GO:0004601; Molecular function: peroxidase activity.
| General |
Signal; -; 0-1; trigger=yes; |
| From: KATG_ECOLI (P13029) |
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Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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ACT_SITE
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106
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106
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Proton acceptor (By similarity)
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H
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METAL
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267
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267
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Iron (heme axial ligand) (By similarity)
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H
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SITE
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102
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102
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Transition state stabilizer (By similarity)
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R
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CROSSLNK
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105
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226
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Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with #{Met-252}) (By similarity)
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W-x*-Y
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CROSSLNK
|
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226
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252
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Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with #{Trp-105}) (By similarity)
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Y-x*-M
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