HAMAP rule MF_02000

General rule information [?]

Accession	MF_02000
Dates	28-JUL-2005 (Created) 20-NOV-2019 (Last updated, Version 15)
Name	HSP20_IbpA
Scope(s)	Bacteria Enterobacterales
Template(s)	P0C054 (IBPA_ECOLI); [ Recover all ]
Triggered by	HAMAP; MF_02000 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	IBPA
Protein name	RecName: Full=Small heat shock protein IbpA; AltName: Full=16 kDa heat shock protein A;
Gene name	Name=ibpA;

Comments [?]

FUNCTION	Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
SUBUNIT	Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations.
SUBCELLULAR LOCATION	Cytoplasm.
SIMILARITY	Belongs to the small heat shock protein (HSP20) family.

Keywords [?]

Gene Ontology [?]

GO:0050821; Biological process:protein stabilization

GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam	PF00011; HSP20; 1;
PROSITE	PS01031; SHSP; 1;

Features [?]

Additional information [?]