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HAMAP rule MF_02115

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General rule information [?]

Accession MF_02115
Dates 16-FEB-2011 (Created)
1-JUN-2023 (Last updated, Version 13)
Name FAD_synth_arch
Scope(s) Archaea
Template(s) Q58579 (RIBL_METJA); Q979C2 (RIBL_THEVO); [ Recover all ]
Triggered by HAMAP; MF_02115 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RIBL
Protein name RecName: Full=FAD synthase;
                 EC=2.7.7.2;
AltName: Full=FMN adenylyltransferase;
AltName: Full=Flavin adenine dinucleotide synthase;
Gene name Name=ribL;

Comments [?]

FUNCTIONCatalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
CATALYTIC ACTIVITY Reaction=ATP + FMN + H(+) = diphosphate + FAD; Xref=Rhea:RHEA:17237, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57692, ChEBI:CHEBI:58210; EC=2.7.7.2;
COFACTOR Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
PATHWAYCofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.
SUBUNITHomodimer.
SIMILARITYBelongs to the archaeal FAD synthase family.

Keywords [?]


Gene Ontology [?]

GO:0003919; Molecular function:FMN adenylyltransferase activity
GO:0005524; Molecular function:ATP binding
GO:0006747; Biological process:FAD biosynthetic process
GO:0046444; Biological process:FMN metabolic process

Cross-references [?]

Pfam PF01467; CTP_transf_2; 1;
Pfam PF01982; CTP-dep_RFKase; 1;
NCBIfam TIGR00125; Cyt_tran_rel; 1;

Features [?]

From: RIBL_THEVO (Q979C2)
Key From To Description Tag Condition FTGroup
BINDING 9 10 /ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"
[VTA]-F
BINDING 14 17 /ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"
H-x-x-H
BINDING 93 93 /ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"
[DN]
BINDING 120 120 /ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"
[YHF]

Additional information [?]

Size range 137-174 amino acids
Related rules None
Fusion Nter: None Cter: None



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