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HAMAP rule MF_03063
General rule information
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| Accession | MF_03063 |
| Dates | 20-NOV-2013 (Created)
1-JUN-2023 (Last updated, Version 10) |
| Name | EF-G_plantC |
| Scope(s) |
Eukaryota Viridiplantae |
| Template(s) | Q9SI75 (EFGC_ARATH); P34811 (EFGC1_SOYBN); [ Recover all ] |
| Triggered by |
HAMAP; MF_03063 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | EFGC |
| Protein name | RecName: Full=Elongation factor G, chloroplastic; Short=cEF-G; |
Comments
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| FUNCTION | Chloroplast-localized elongation factor EF-G involved in protein synthesis in plastids. Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl- tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. |
| PATHWAY | Protein biosynthesis; polypeptide chain elongation. |
| SUBCELLULAR LOCATION | Plastid, chloroplast. |
| case not <AnyFeature:TransitC> | |
| MISCELLANEOUS | This protein may be expected to contain an N-terminal transit peptide but none has been predicted. |
| end case | |
| SIMILARITY | Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. |
Keywords
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Gene Ontology
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| GO:0003746; Molecular function:translation elongation factor activity |
| GO:0003924; Molecular function:GTPase activity |
| GO:0005525; Molecular function:GTP binding |
| GO:0006414; Biological process:translational elongation |
| GO:0009507; Cellular component:chloroplast |
Cross-references
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| PROSITE | PS00301; G_TR_1; 1; |
| PROSITE | PS51722; G_TR_2; 1; |
| Pfam | PF00679; EFG_C; 1; |
| Pfam | PF14492; EFG_II; 1; |
| Pfam | PF03764; EFG_IV; 1; |
| Pfam | PF00009; GTP_EFTU; 1; |
| Pfam | PF03144; GTP_EFTU_D2; 1; |
| PRINTS | PR00315; ELONGATNFCT; 1; |
| NCBIfam | TIGR00484; EF-G; 1; |
| NCBIfam | TIGR00231; small_GTP; 1; |
| General | TransitC; -; 0-1; |
Features
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| From: EFGC_ARATH (Q9SI75) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 103 | 110 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" |
[AS]-H-[IV]-D-[AS]-G-K-T | ||||||||
| BINDING | 167 | 171 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" |
D-T-P-G-H | ||||||||
| BINDING | 221 | 224 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" |
N-K-x-D | ||||||||
Additional information
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| Size range | 681-840 amino acids |
| Related rules |
MF_03061 |
| Fusion | Nter: None Cter: None |