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HAMAP rule MF_03111

General rule information [?]

Accession	MF_03111
Dates	8-OCT-2009 (Created) 20-NOV-2019 (Last updated, Version 6)
Name	Coq4
Scope(s)	Eukaryota
Template(s)	O13525 (COQ4_YEAST); [ Recover all ]
Triggered by	HAMAP; MF_03111 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	COQ4
case <OC:Fungi> or <OC:Caenorhabditis>
Protein name	RecName: Full=Ubiquinone biosynthesis protein , mitochondrial; AltName: Full=Coenzyme Q biosynthesis protein 4;
else
Protein name	RecName: Full=Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; AltName: Full=Coenzyme Q biosynthesis protein 4 homolog;
end case
case <OC:Vertebrata> or <OC:Fungi> or <OC:Dictyostelium>
Gene name	Name=COQ4;
else case <OC:Caenorhabditis>
Gene name	Name=coq-4;
end case

Comments [?]

case <OC:Saccharomyces>
FUNCTION	Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of COQ3, COQ4, COQ6, COQ7 and COQ9 polypeptides.
else
FUNCTION	Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
end case
PATHWAY	Cofactor biosynthesis; ubiquinone biosynthesis.
case <OC:Saccharomyces>
SUBUNIT	Component of a multi-subunit COQ enzyme complex, composed of at least @gn(COQ3), @gn(COQ4), @gn(COQ5), @gn(COQ6), @gn(COQ7) and @gn(COQ9). Interacts with COQ3.
else case <OC:Vertebrata> or <OC:Fungi> and not <OC:Saccharomyces>
SUBUNIT	Component of a multi-subunit COQ enzyme complex, composed of at least @gn(COQ3), @gn(COQ4), @gn(COQ5), @gn(COQ6), @gn(COQ7) and @gn(COQ9).
else
SUBUNIT	Component of a multi-subunit COQ enzyme complex.
end case
SUBCELLULAR LOCATION	Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
case not <AnyFeature:TransitM>
MISCELLANEOUS	This protein may be expected to contain an N-terminal transit peptide but none has been predicted.
end case
SIMILARITY	Belongs to the COQ4 family.

Keywords [?]

Gene Ontology [?]

GO:0031314; Cellular component:extrinsic component of mitochondrial inner membrane

GO:0006744; Biological process:ubiquinone biosynthetic process

Cross-references [?]

Pfam	PF05019; Coq4; 1;
General	TransitM; -; 0-1;

Features [?]

Additional information [?]