HAMAP rule MF_03122
General rule information
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| Accession | MF_03122 |
| Dates | 27-OCT-2009 (Created)
22-SEP-2023 (Last updated, Version 8) |
| Name | Ribosomal_eS1_euk |
| Scope(s) |
Eukaryota |
| Template(s) | P61247 (RS3A_HUMAN); P33442 (RS3A1_YEAST); [ Recover all ] |
| Triggered by |
HAMAP; MF_03122 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | RS3A |
| Protein name | RecName: Full=Small ribosomal subunit protein eS1; |
| case <OC:Vertebrata> | |
| Gene name | Name=RPS3A; |
| else case <OC:Caenorhabditis> | |
| Gene name | Name=rps-1; |
| else case <OC:Drosophilidae> | |
| Gene name | Name=RpS3A; |
| else case <OC:Fungi> | |
| Gene name | Name=RPS1; |
| end case | |
Comments
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| case <OC:Mammalia> | |
| FUNCTION | May play a role during erythropoiesis through regulation of transcription factor @gn(DDIT3). |
| else case <OC:Drosophilidae> | |
| FUNCTION | Essential for oogenesis; required for late follicle cell development. |
| end case | |
| case <OC:Mammalia> | |
| SUBUNIT | Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs. Binds with high affinity to @gn(IPO4). Interacts with @gn(DDIT3). |
| else case <OC:Metazoa> and not <OC:Mammalia> | |
| SUBUNIT | Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). |
| else | |
| SUBUNIT | Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). |
| end case | |
| case <OC:Mammalia> | |
| SUBCELLULAR LOCATION | Cytoplasm. Nucleus. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. |
| else | |
| SUBCELLULAR LOCATION | Cytoplasm. |
| end case | |
| SIMILARITY | Belongs to the eukaryotic ribosomal protein eS1 family. |
Keywords
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| Ribonucleoprotein | |
| Ribosomal protein | |
| case <OC:Mammalia> or <OC:Drosophilidae> | |
| Differentiation | |
| end case | |
| case <OC:Drosophilidae> | |
| Developmental protein | |
| Oogenesis | |
| end case | |
| Cytoplasm | |
| case <OC:Mammalia> | |
| Nucleus | |
| end case | |
| case <FTTag:acetyl> | |
| Acetylation | |
| end case | |
Gene Ontology
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| GO:0022627; Cellular component:cytosolic small ribosomal subunit |
| GO:0003735; Molecular function:structural constituent of ribosome |
| GO:0006412; Biological process:translation |
Cross-references
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Features
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| From: RS3A_HUMAN (P61247) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| INIT_MET | 1 | 1 | /note="Removed" | M | ||||||||
| From: RS3A1_YEAST (P33442) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| case <OC:Fungi> | ||||||||||||
| MOD_RES | 2 | 2 | /note="N-acetylalanine; partial" | acetyl | A | |||||||
| end case | ||||||||||||
Additional information
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| Size range | 189-273 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |