HAMAP rule MF_00001

General rule information [?]

Accession	MF_00001
Dates	1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 36)
Name	Asp_carb_tr
Scope(s)	Bacteria Archaea
Template(s)	P0A786 (PYRB_ECOLI); P05654 (PYRB_BACSU); Q58976 (PYRB_METJA); Q55338 (PYRB_SULAC); [ Recover all ]
Triggered by	HAMAP; MF_00001 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	PYRB
Protein name	RecName: Full=Aspartate carbamoyltransferase; EC=2.1.3.2; AltName: Full=Aspartate transcarbamylase; Short=ATCase;
Gene name	Name=pyrB;

Comments [?]

CATALYTIC ACTIVITY	Reaction=carbamoyl phosphate + L-aspartate = H(+) + N-carbamoyl-L- aspartate + phosphate; Xref=Rhea:RHEA:20013, ChEBI:CHEBI:15378, ChEBI:CHEBI:29991, ChEBI:CHEBI:32814, ChEBI:CHEBI:43474, ChEBI:CHEBI:58228; EC=2.1.3.2;
PATHWAY	Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.
case <OC:Archaea>
SUBUNIT	Heterooligomer of catalytic and regulatory chains.
end case
SIMILARITY	Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

Keywords [?]

Gene Ontology [?]

GO:0004070; Molecular function:aspartate carbamoyltransferase activity

GO:0006221; Biological process:pyrimidine nucleotide biosynthetic process

Cross-references [?]

Features [?]

Additional information [?]