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Annotation rule MF_00001
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General rule information [?]

Accession MF_00001
Dates 1-JUN-2001 (Created)
20-NOV-2019 (Last updated, Version 35)
Name Asp_carb_tr
Scope
Bacteria
Archaea
Templates P0A786 (PYRB_ECOLI); P05654 (PYRB_BACSU); Q58976 (PYRB_METJA); Q55338 (PYRB_SULAC): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
PYRB
Protein name
RecName: Full=Aspartate carbamoyltransferase;
EC 2.1.3.2;
AltName: Full=Aspartate transcarbamylase;
Short=ATCase;
Gene name
pyrB

Comments [?]

Catalytic activity RHEA:20013: carbamoyl phosphate + L-aspartate = H(+) + N-carbamoyl-L-aspartate + phosphate
EC 2.1.3.2
Pathway Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.
case <OC:Archaea>
Subunit Heterooligomer of catalytic and regulatory chains.
end case
Similarity Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

Keywords [?]

Pyrimidine biosynthesis
Transferase

Gene Ontology [?]

GO:0004070; Molecular function: aspartate carbamoyltransferase activity.
GO:0006221; Biological process: pyrimidine nucleotide biosynthetic process.

Cross-references [?]

Pfam PF00185; OTCace; 1;
TIGRFAMs TIGR00670; asp_carb_tr; 1;
PROSITE PS00097; CARBAMOYLTRANSFERASE; 1;

Additional information [?]

Size range 291-475 amino acids
Related rules None
Fusion Nter: None; Cter: MF_00002 (pyrI)


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