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HAMAP rule MF_00001

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General rule information [?]

Accession MF_00001
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 36)
Name Asp_carb_tr
Scope(s) Bacteria
Template(s) P0A786 (PYRB_ECOLI); P05654 (PYRB_BACSU); Q58976 (PYRB_METJA); Q55338 (PYRB_SULAC); [ Recover all ]
Triggered by HAMAP; MF_00001 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier PYRB
Protein name RecName: Full=Aspartate carbamoyltransferase;
AltName: Full=Aspartate transcarbamylase;
Gene name Name=pyrB;

Comments [?]

CATALYTIC ACTIVITY Reaction=carbamoyl phosphate + L-aspartate = H(+) + N-carbamoyl-L- aspartate + phosphate; Xref=Rhea:RHEA:20013, ChEBI:CHEBI:15378, ChEBI:CHEBI:29991, ChEBI:CHEBI:32814, ChEBI:CHEBI:43474, ChEBI:CHEBI:58228; EC=;
PATHWAYPyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.
case <OC:Archaea>
SUBUNITHeterooligomer of catalytic and regulatory chains.
end case
SIMILARITYBelongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

Keywords [?]

Gene Ontology [?]

GO:0004070; Molecular function:aspartate carbamoyltransferase activity
GO:0006221; Biological process:pyrimidine nucleotide biosynthetic process

Cross-references [?]

Pfam PF00185; OTCace; 1;
NCBIfam TIGR00670; asp_carb_tr; 1;

Features [?]

Additional information [?]

Size range 291-475 amino acids
Related rules None
Fusion Nter: None Cter: MF_00002 (pyrI)

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