HAMAP rule MF_00007
General rule information
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Accession | MF_00007 |
Dates | 1-JUN-2001 (Created)
28-APR-2022 (Last updated, Version 25) |
Name | DNA_primase_DnaG_arc |
Scope(s) |
Archaea |
Template(s) | P95980 (DNAG_SACS2); [ Recover all ] |
Triggered by |
HAMAP; MF_00007 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | DNAG |
Protein name | RecName: Full=DNA primase DnaG; EC=2.7.7.101; |
Gene name | Name=dnaG; |
Comments
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case <OC:Halobacteriales> or <OC:Methanococcales> or <OC:Methanomicrobiales> | |
FUNCTION | RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. |
SUBUNIT | Forms a ternary complex with MCM helicase and DNA. |
else | |
FUNCTION | RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. |
SUBUNIT | Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex. |
end case | |
CATALYTIC ACTIVITY | Reaction=ssDNA + n NTP = ssDNA/pppN(pN)n-1 hybrid + (n-1) diphosphate.; EC=2.7.7.101; |
SIMILARITY | Belongs to the archaeal DnaG primase family. |
Keywords
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DNA replication | |
DNA-directed RNA polymerase | |
Nucleotidyltransferase | |
Primosome | |
Transcription | |
Transferase | |
case not <OC:Halobacteriales> and not <OC:Methanococcales> and not <OC:Methanomicrobiales> | |
Exosome | |
end case |
Gene Ontology
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GO:0003896; Molecular function:DNA primase activity |
GO:0006269; Biological process:DNA replication, synthesis of RNA primer |
Cross-references
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Features
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Additional information
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Size range | 355-603 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |