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HAMAP rule MF_00007

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General rule information [?]

Accession MF_00007
Dates 1-JUN-2001 (Created)
28-APR-2022 (Last updated, Version 25)
Name DNA_primase_DnaG_arc
Scope(s) Archaea
Template(s) P95980 (DNAG_SACS2); [ Recover all ]
Triggered by HAMAP; MF_00007 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier DNAG
Protein name RecName: Full=DNA primase DnaG;
                 EC=2.7.7.101;
Gene name Name=dnaG;

Comments [?]

case <OC:Halobacteriales> or <OC:Methanococcales> or <OC:Methanomicrobiales>
FUNCTIONRNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
SUBUNITForms a ternary complex with MCM helicase and DNA.
else
FUNCTIONRNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
SUBUNITForms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
end case
CATALYTIC ACTIVITY Reaction=ssDNA + n NTP = ssDNA/pppN(pN)n-1 hybrid + (n-1) diphosphate.; EC=2.7.7.101;
SIMILARITYBelongs to the archaeal DnaG primase family.

Keywords [?]

DNA replication
DNA-directed RNA polymerase
Nucleotidyltransferase
Primosome
Transcription
Transferase
case not <OC:Halobacteriales> and not <OC:Methanococcales> and not <OC:Methanomicrobiales>
Exosome
end case

Gene Ontology [?]

GO:0003896; Molecular function:DNA primase activity
GO:0006269; Biological process:DNA replication, synthesis of RNA primer

Cross-references [?]

Pfam PF01751; Toprim; 1;
PROSITE PS50880; TOPRIM; 1;

Features [?]


Additional information [?]

Size range 355-603 amino acids
Related rules None
Fusion Nter: None Cter: None



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