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HAMAP rule MF_00007

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General rule information [?]

Accession MF_00007
Dates 1-JUN-2001 (Created)
28-APR-2022 (Last updated, Version 25)
Name DNA_primase_DnaG_arc
Scope
Archaea
Template P95980 (DNAG_SACS2)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
DNAG
Protein name
RecName: Full=DNA primase DnaG;
EC 2.7.7.101;
Gene name
dnaG

Comments [?]

case <OC:Halobacteriales> or <OC:Methanococcales> or <OC:Methanomicrobiales>
Function RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
Subunit Forms a ternary complex with MCM helicase and DNA.
else
Function RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
Subunit Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
end case
Catalytic activity Reaction=ssDNA + n NTP = ssDNA/pppN(pN)n-1 hybrid + (n-1) diphosphate.; EC=2.7.7.101;
Similarity Belongs to the archaeal DnaG primase family.

Keywords [?]

case not <OC:Halobacteriales> and not <OC:Methanococcales> and not <OC:Methanomicrobiales>
end case

Gene Ontology [?]

GO:0003896; Molecular function: DNA primase activity.
GO:0006269; Biological process: DNA replication, synthesis of RNA primer.

Cross-references [?]

Pfam PF01751; Toprim; 1;
PROSITE PS50880; TOPRIM; 1; trigger=PRU00995;

Additional information [?]

Size range 355-603 amino acids
Related rules None
Fusion None