HAMAP rule MF_00025

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_00025
Accession	MF_00025
Dates	1-JUN-2001 (Created) 20-MAR-2025 (Last updated, Version 29)
Name	RNApol_Rpo5_RPB5
Scope(s)	Archaea
Template(s)	Q58443 (RPO5_METJA); O27122 (RPO5_METTH); B8YB60 (RPO5_SACSH); P11521 (RPO5_SULAC); Q980Q9 (RPO5_SACS2); [ Recover all ]
Triggered by	HAMAP; MF_00025 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	RPO5
Protein name	RecName: Full=DNA-directed RNA polymerase subunit Rpo5; EC=2.7.7.6; AltName: Full=DNA-directed RNA polymerase subunit H;
Gene name	Name=rpo5; Synonyms=rpoH;

Comments [?]

FUNCTION	DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
CATALYTIC ACTIVITY	Reaction=RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate; Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA- COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395; EC=2.7.7.6;
SUBUNIT	Part of the RNA polymerase complex.
SUBCELLULAR LOCATION	Cytoplasm.
SIMILARITY	Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.

Keywords [?]

Gene Ontology [?]

GO:0005737; Cellular component:cytoplasm

GO:0003899; Molecular function:DNA-directed RNA polymerase activity

GO:0006351; Biological process:DNA-templated transcription

Cross-references [?]

Pfam	PF01191; RNA_pol_Rpb5_C; 1;
PROSITE	PS01110; RNA_POL_H_23KD; 1;

Features [?]

Additional information [?]