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Annotation rule MF_00028
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General rule information [?]

Accession MF_00028
Dates 1-JUN-2001 (Created)
11-JAN-2021 (Last updated, Version 28)
Name CobQ
Scope
Bacteria
Archaea
Template P29932 (COBQ_SINSX)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
COBQ
case <OC:Bacteria>
Protein name
RecName: Full=Cobyric acid synthase;
end case
case <OC:Archaea>
Protein name
RecName: Full=Probable cobyric acid synthase;
end case
Gene name
cobQ

Comments [?]

Function Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
Pathway Cofactor biosynthesis; adenosylcobalamin biosynthesis.
Similarity Belongs to the CobB/CobQ family. CobQ subfamily.

Keywords [?]

Cobalamin biosynthesis
Glutamine amidotransferase

Gene Ontology [?]

GO:0015420; Molecular function: ABC-type vitamin B12 transporter activity.

Cross-references [?]

Pfam PF01656; CbiA; 1;
PF07685; GATase_3; 1;
TIGRFAMs TIGR00313; CobQ; 1;
PROSITE PS51274; GATASE_COBBQ; 1; trigger=PRU00606;

Features [?]

From: COBQ_SINSX (P29932)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     333     333       Nucleophile     C  
ACT_SITE     430     430             H  

Additional information [?]

Size range 464-543 amino acids
Related rules MF_00027 (COBB)
Fusion None
Comments Called cbiP in Salmonella


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