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HAMAP rule MF_00030

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General rule information [?]

Accession MF_00030
Dates 1-JUN-2001 (Created)
20-NOV-2019 (Last updated, Version 26)
Name dGTPase_type1
Scope(s) Bacteria
Template(s) P15723 (DGTP_ECOLI); Q59827 (DGTP_SHIBO); [ Recover all ]
Triggered by HAMAP; MF_00030 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier DGTP
case <OC:Enterobacterales>
Protein name RecName: Full=Deoxyguanosinetriphosphate triphosphohydrolase;
                 Short=dGTP triphosphohydrolase;
Protein name RecName: Full=Probable deoxyguanosinetriphosphate triphosphohydrolase;
                 Short=dGTP triphosphohydrolase;
end case
Gene name Name=dgt;

Comments [?]

FUNCTIONdGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.
CATALYTIC ACTIVITY Reaction=dGTP + H2O = 2'-deoxyguanosine + H(+) + triphosphate; Xref=Rhea:RHEA:15193, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:17172, ChEBI:CHEBI:18036, ChEBI:CHEBI:61429; EC=;
COFACTOR Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
case <OC:Enterobacterales>
end case
SIMILARITYBelongs to the dGTPase family. Type 1 subfamily.
case not <OC:Enterobacterales>
CAUTIONAs this bacterium is not an Enterobacterale, this protein may not have a true dGTPase activity.
end case

Keywords [?]

Gene Ontology [?]

GO:0008832; Molecular function:dGTPase activity
GO:0000287; Molecular function:magnesium ion binding

Cross-references [?]

Pfam PF01966; HD; 1;
PROSITE PS51831; HD; 1;

Features [?]

Additional information [?]

Size range 498-533 amino acids
Related rules None
Fusion Nter: None Cter: None

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