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Annotation rule MF_00063
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General rule information [?]

Accession MF_00063
Dates 1-JUN-2001 (Created)
20-NOV-2019 (Last updated, Version 31)
Name CysH
Template P17854 (CYSH_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Phosphoadenosine phosphosulfate reductase;
AltName: Full=3'-phosphoadenylylsulfate reductase;
AltName: Full=PAPS reductase, thioredoxin dependent;
AltName: Full=PAPS sulfotransferase;
AltName: Full=PAdoPS reductase;
Gene name

Comments [?]

Function Reduction of activated sulfate into sulfite.
Catalytic activity RHEA:11724: [thioredoxin]-disulfide + adenosine 3',5'-bisphosphate + 2 H(+) + sulfite = 3'-phosphoadenylyl sulfate + [thioredoxin]-dithiol
Pathway Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3.
Subcellular location Cytoplasm.
Similarity Belongs to the PAPS reductase family. CysH subfamily.

Keywords [?]

Gene Ontology [?]

GO:0004604; Molecular function: phosphoadenylyl-sulfate reductase (thioredoxin) activity.
GO:0019379; Biological process: sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin).
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF01507; PAPS_reduct; 1;
TIGRFAMs TIGR00434; CysH; 1;

Additional information [?]

Size range 226-267 amino acids
Related rules None
Fusion None