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Annotation rule MF_00069
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General rule information [?]

Accession MF_00069
Dates 1-JUN-2001 (Created)
20-NOV-2019 (Last updated, Version 38)
Name Hydroxylam_reduct
Templates P31101 (HCP_DESVH); Q01770 (HCP_DESDA); P75825 (HCP_ECOLI); Q6WRT6 (HCP_RHOCA): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Hydroxylamine reductase;
AltName: Full=Hybrid-cluster protein;
AltName: Full=Prismane protein;
Gene name

Comments [?]

Function Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
Catalytic activity RHEA:22052: A + H2O + NH4(+) = AH2 + H(+) + hydroxylamine
case <OC:Gammaproteobacteria> and <FTGroup:1>
Cofactor [2Fe-2S] cluster
Note: Binds 1 [2Fe-2S] cluster.
end case
case not <OC:Gammaproteobacteria> and <FTGroup:2>
Cofactor [4Fe-4S] cluster
Note: Binds 1 [4Fe-4S] cluster.
end case
case <FTGroup:3>
Cofactor hybrid [4Fe-2O-2S] cluster
Note: Binds 1 hybrid [4Fe-2O-2S] cluster.
end case
Subcellular location Cytoplasm.
Similarity Belongs to the HCP family.

Keywords [?]

case <FTGroup:1> or <FTGroup:2> or <FTGroup:3>
end case
case <OC:Gammaproteobacteria> and <FTGroup:1>
end case
case not <OC:Gammaproteobacteria> and <FTGroup:2>
end case

Gene Ontology [?]

GO:0005737; Cellular component: cytoplasm.
GO:0050418; Molecular function: hydroxylamine reductase activity.
GO:0051536; Molecular function: iron-sulfur cluster binding.

Cross-references [?]

Pfam PF03063; Prismane; 1;
TIGRFAMs TIGR01703; hybrid_clust; 1;

Features [?]

case <OC:Gammaproteobacteria>
From: HCP_ECOLI (P75825)
Key     From     To       Description   Tag   Condition   FTGroup
METAL     3     3       Iron-sulfur (2Fe-2S)     C   1
METAL     6     6       Iron-sulfur (2Fe-2S)     C   1
METAL     18     18       Iron-sulfur (2Fe-2S)     C   1
METAL     25     25       Iron-sulfur (2Fe-2S)     C   1
end case
case not <OC:Gammaproteobacteria>
From: HCP_DESVH (P31101)
METAL     3     3       Iron-sulfur (4Fe-4S)     C   2
METAL     6     6       Iron-sulfur (4Fe-4S)     C   2
METAL     15     15       Iron-sulfur (4Fe-4S)     C   2
METAL     21     21       Iron-sulfur (4Fe-4S)     C   2
end case
METAL     244     244       Iron-oxo-sulfur (4Fe-2O-2S); via tele nitrogen     H   3
METAL     268     268       Iron-oxo-sulfur (4Fe-2O-2S)     E   3
METAL     312     312       Iron-oxo-sulfur (4Fe-2O-2S)     C   3
METAL     406     406       Iron-oxo-sulfur (4Fe-2O-2S); via persulfide group     C   3
METAL     434     434       Iron-oxo-sulfur (4Fe-2O-2S)     C   3
METAL     459     459       Iron-oxo-sulfur (4Fe-2O-2S)     C   3
METAL     494     494       Iron-oxo-sulfur (4Fe-2O-2S)     E   3
METAL     496     496       Iron-oxo-sulfur (4Fe-2O-2S)     K   3
MOD_RES     406     406       Cysteine persulfide     C  

Additional information [?]

Size range 427-570 amino acids
Related rules None
Fusion None
Comments Possible wrong start in THEMA and ACIFR. Deleted domain in THEMA/METTH.