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HAMAP rule MF_00081

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General rule information [?]

Accession MF_00081
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 26)
Name HrcA
Scope(s) Bacteria
Template(s) P25499 (HRCA_BACSU); [ Recover all ]
Triggered by HAMAP; MF_00081 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier HRCA
Protein name RecName: Full=Heat-inducible transcription repressor HrcA;
Gene name Name=hrcA;

Comments [?]

FUNCTIONNegative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
SIMILARITYBelongs to the HrcA family.

Keywords [?]

Gene Ontology [?]

GO:0045892; Biological process:negative regulation of DNA-templated transcription

Cross-references [?]

Pfam PF01628; HrcA; 1;
NCBIfam TIGR00331; HrcA; 1;

Features [?]

Additional information [?]

Size range 264-398 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments Possible wrong starts in a number of sequences. See: MEDLINE=20023017; PubMed=10555317; Ahmad S., Selvapandiyan A., Bhatnagar R.K.; "A protein-based phylogenetic tree for gram-positive bacteria derived from hrcA, a unique heat-shock regulatory gene."; Int. J. Syst. Bacteriol. 49:1387-1394(1999).

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