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Annotation rule MF_00081
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General rule information [?]

Accession MF_00081
Dates 1-JUN-2001 (Created)
20-NOV-2019 (Last updated, Version 24)
Name HrcA
Scope
Bacteria
Template P25499 (HRCA_BACSU)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
HRCA
Protein name
RecName: Full=Heat-inducible transcription repressor HrcA;
Gene name
hrcA

Comments [?]

Function Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.
Similarity Belongs to the HrcA family.

Keywords [?]


Gene Ontology [?]

GO:0045892; Biological process: negative regulation of transcription, DNA-templated.

Cross-references [?]

Pfam PF01628; HrcA; 1;
TIGRFAMs TIGR00331; HrcA; 1;

Additional information [?]

Size range 264-398 amino acids
Related rules None
Fusion None
Comments Possible wrong starts in a number of sequences. See: MEDLINE=20023017; PubMed=10555317; Ahmad S., Selvapandiyan A., Bhatnagar R.K.; "A protein-based phylogenetic tree for gram-positive bacteria derived from hrcA, a unique heat-shock regulatory gene."; Int. J. Syst. Bacteriol. 49:1387-1394(1999).