HAMAP rule MF_00093

General rule information [?]

Accession	MF_00093
Dates	1-JUN-2001 (Created) 20-NOV-2019 (Last updated, Version 21)

Name

Rel_fac_1

Scope

Bacteria

Template

P0A7I0 (RF1_ECOLI)

Triggered by

HAMAP; MF_00093 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

RF1

Protein name

RecName:		Full=Peptide chain release factor 1;
		Short=RF-1;

Gene name

prfA

Comments [?]

Function	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
Subcellular location	Cytoplasm.

case <FT:1>

Ptm	Methylated by PrmC. Methylation increases the termination efficiency of RF1.

end case

Similarity

Belongs to the prokaryotic/mitochondrial release factor family.

Keywords [?]

Cytoplasm
Protein biosynthesis

case <FT:1>

Methylation

end case

Gene Ontology [?]

GO:0016149; Molecular function: translation release factor activity, codon specific.
GO:0006415; Biological process: translational termination.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam	PF00472; RF-1; 1;
TIGRFAMs	TIGR00019; PrfA; 1;
PROSITE	PS00745; RF_PROK_I; 1;

Features [?]

From: RF1_ECOLI (P0A7I0)

Key From To Description Tag Condition FTGroup

MOD_RES 235 235 N5-methylglutamine Q

Additional information [?]

Size range	342-375 amino acids
Related rules	MF_00094 (RF2)
Fusion	None

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