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HAMAP rule MF_00093

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General rule information [?]

Accession MF_00093
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 22)
Name Rel_fac_1
Scope(s) Bacteria
Template(s) P0A7I0 (RF1_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00093 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RF1
Protein name RecName: Full=Peptide chain release factor 1;
Gene name Name=prfA;

Comments [?]

FUNCTIONPeptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
case <FT:1>
PTMMethylated by PrmC. Methylation increases the termination efficiency of RF1.
end case
SIMILARITYBelongs to the prokaryotic/mitochondrial release factor family.

Keywords [?]

Gene Ontology [?]

GO:0016149; Molecular function:translation release factor activity, codon specific
GO:0006415; Biological process:translational termination
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF00472; RF-1; 1;
NCBIfam TIGR00019; PrfA; 1;

Features [?]

From: RF1_ECOLI (P0A7I0)
Key From To Description Tag Condition FTGroup
MOD_RES 235 235 /note="N5-methylglutamine" Q

Additional information [?]

Size range 342-375 amino acids
Related rules MF_00094
Fusion Nter: None Cter: None

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