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Annotation rule MF_00093
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General rule information [?]

Accession MF_00093
Dates 1-JUN-2001 (Created)
20-NOV-2019 (Last updated, Version 21)
Name Rel_fac_1
Scope
Bacteria
Template P0A7I0 (RF1_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
RF1
Protein name
RecName: Full=Peptide chain release factor 1;
Short=RF-1;
Gene name
prfA

Comments [?]

Function Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
Subcellular location Cytoplasm.
case <FT:1>
Ptm Methylated by PrmC. Methylation increases the termination efficiency of RF1.
end case
Similarity Belongs to the prokaryotic/mitochondrial release factor family.

Keywords [?]

case <FT:1>
end case

Gene Ontology [?]

GO:0016149; Molecular function: translation release factor activity, codon specific.
GO:0006415; Biological process: translational termination.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF00472; RF-1; 1;
TIGRFAMs TIGR00019; PrfA; 1;
PROSITE PS00745; RF_PROK_I; 1;

Features [?]

From: RF1_ECOLI (P0A7I0)
Key     From     To       Description   Tag   Condition   FTGroup
MOD_RES     235     235       N5-methylglutamine     Q  

Additional information [?]

Size range 342-375 amino acids
Related rules MF_00094 (RF2)
Fusion None