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HAMAP rule MF_00117

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General rule information [?]

Accession MF_00117
Dates 1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 20)
Name HslO
Scope(s) Bacteria
Template(s) P0A6Y5 (HSLO_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00117 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier HSLO
Protein name RecName: Full=33 kDa chaperonin;
AltName: Full=Heat shock protein 33 homolog;
Gene name Name=hslO;

Comments [?]

FUNCTIONRedox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
PTMUnder oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.
SIMILARITYBelongs to the HSP33 family.

Keywords [?]

Gene Ontology [?]

GO:0051082; Molecular function:unfolded protein binding
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF01430; HSP33; 1;

Features [?]

Key From To Description Tag Condition FTGroup
DISULFID 230 232 /note="Redox-active" C-x-C
DISULFID 263 266 /note="Redox-active" C-x(2)-C

Additional information [?]

Size range 281-341 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments Possible wrong start in AQUAE and DEIRA

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