HAMAP rule MF_00117

General rule information [?]

Accession	MF_00117
Dates	1-JUN-2001 (Created) 18-NOV-2019 (Last updated, Version 20)

Name

HslO

Scope

Bacteria

Template

P0A6Y5 (HSLO_ECOLI)

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

HSLO

Protein name

RecName:		Full=33 kDa chaperonin;
AltName:		Full=Heat shock protein 33 homolog;
		Short=HSP33;

Gene name

hslO

Comments [?]

Function	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
Subcellular location	Cytoplasm.
Ptm	Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.
Similarity	Belongs to the HSP33 family.

Keywords [?]

Gene Ontology [?]

GO:0051082; Molecular function: unfolded protein binding.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam	PF01430; HSP33; 1;

Features [?]

From: HSLO_ECOLI (P0A6Y5)

Key From To Description Tag Condition FTGroup

DISULFID 230 232 Redox-active C-x-C

DISULFID 263 266 Redox-active C-x(2)-C

Additional information [?]

Size range	281-341 amino acids
Related rules	None
Fusion	None
Comments	Possible wrong start in AQUAE and DEIRA