HAMAP logo

HAMAP rule MF_00119

Send feedback

General rule information [?]

Accession MF_00119
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 25)
Name eIF_2_gamma
Scope(s) Archaea
Template(s) Q980A5 (IF2G_SACS2); Q8U082 (IF2G_PYRFU); Q9V1G0 (IF2G_PYRAB); O29663 (IF2G_ARCFU); Q58657 (IF2G_METJA); [ Recover all ]
Triggered by HAMAP; MF_00119 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier IF2G
Protein name RecName: Full=Translation initiation factor 2 subunit gamma;
AltName: Full=aIF2-gamma;
AltName: Full=eIF-2-gamma;
Gene name Name=eif2g;

Comments [?]

FUNCTIONeIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
CATALYTIC ACTIVITY Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565, ChEBI:CHEBI:43474, ChEBI:CHEBI:58189; EC=;
COFACTOR Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
SUBUNITHeterotrimer composed of an alpha, a beta and a gamma chain.
SIMILARITYBelongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.

Keywords [?]

Gene Ontology [?]

GO:0005525; Molecular function:GTP binding
GO:0003746; Molecular function:translation elongation factor activity

Cross-references [?]

Pfam PF09173; eIF2_C; 1;
Pfam PF00009; GTP_EFTU; 1;
NCBIfam TIGR03680; eif2g_arch; 1;
NCBIfam TIGR00231; small_GTP; 1;
PROSITE PS51722; G_TR_2; 1;

Features [?]

From: IF2G_SACS2 (Q980A5)
Key From To Description Tag Condition FTGroup
BINDING 19 24 /ligand="GTP"
BINDING 149 152 /ligand="GTP"
BINDING 184 186 /ligand="GTP"
BINDING 19 19 /ligand="Mg(2+)"
BINDING 23 23 /ligand="Mg(2+)"
BINDING 44 44 /ligand="Mg(2+)"
BINDING 46 46 /ligand="Mg(2+)"
BINDING 59 59 /ligand="Zn(2+)"
C 1
BINDING 62 62 /ligand="Zn(2+)"
C 1
BINDING 74 74 /ligand="Zn(2+)"
C 1
BINDING 77 77 /ligand="Zn(2+)"
C 1

Additional information [?]

Size range 408-443 amino acids
Related rules None
Fusion Nter: None Cter: None

View rule in raw text format (no links)