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Annotation rule MF_00119 |
Accession | MF_00119 |
Dates | 1-JUN-2001 (Created) 30-JAN-2020 (Last updated, Version 22) |
Name | eIF_2_gamma |
Scope | Archaea |
Templates | Q980A5 (IF2G_SACS2); Q8U082 (IF2G_PYRFU); Q9V1G0 (IF2G_PYRAB); O29663 (IF2G_ARCFU); Q58657 (IF2G_METJA): [Recover all] |
Triggered by |
Identifier |
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Protein name |
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Gene name |
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Function | eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. |
Catalytic activity | RHEA:19669: GTP + H2O = GDP + H(+) + phosphate
EC 3.6.5.3 |
Cofactor | Mg(2+) |
Subunit | Heterotrimer composed of an alpha, a beta and a gamma chain. |
Similarity | Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. |
Pfam | PF09173; eIF2_C; 1; |
PF00009; GTP_EFTU; 1; | |
TIGRFAMs | TIGR03680; eif2g_arch; 1; |
TIGR00231; small_GTP; 1; | |
PROSITE | PS51722; G_TR_2; 1; trigger=PRU01059; |
From: IF2G_SACS2 (Q980A5) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
NP_BIND | 19 | 24 | GTP | D-H-G-K-[ST]-[ST] | ||||||||
NP_BIND | 149 | 152 | GTP | N-K-[VI]-[DE] | ||||||||
NP_BIND | 184 | 186 | GTP | S-A-x | ||||||||
METAL | 19 | 19 | Magnesium 2 | D | ||||||||
METAL | 23 | 23 | Magnesium 1 | [ST] | ||||||||
METAL | 44 | 44 | Magnesium 2; via carbonyl oxygen | G | ||||||||
METAL | 46 | 46 | Magnesium 1 | [ST] | ||||||||
METAL (Optional) | 59 | 59 | Zinc | C | 1 | |||||||
METAL (Optional) | 62 | 62 | Zinc | C | 1 | |||||||
METAL (Optional) | 74 | 74 | Zinc | C | 1 | |||||||
METAL (Optional) | 77 | 77 | Zinc | C | 1 |
Size range | 408-443 amino acids |
Related rules | None |
Fusion | None |