HAMAP rule MF_00121
General rule information
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Accession | MF_00121 |
Dates | 1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 28) |
Name | GatB |
Scope | Bacteria
Archaea |
Templates | O30509 (GATB_BACSU); Q9LCX2 (GATB_THET8); O27341 (GATB_METTH): [Recover all] |
case <OC:Bacteria> or <OC:Archaea>
Triggered by |
end case
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln). |
Catalytic activity | RHEA:17521: ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate |
RHEA:14513: ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate | |
Subunit | Heterotrimer of A, B and C subunits. |
Similarity | Belongs to the GatB/GatE family. GatB subfamily. |
Keywords
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Gene Ontology
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GO:0050567; Molecular function: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity.
GO:0006412; Biological process: translation.
GO:0006412; Biological process: translation.
Cross-references
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Pfam | PF02934; GatB_N; 1; |
PF02637; GatB_Yqey; 1; | |
NCBIfam | TIGR00133; GatB; 1; |
PROSITE | PS01234; GATB; 1; |
Additional information
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Size range | 449-517 amino acids |
Related rules | MF_00588 (GATE) |
Fusion | Nter: MF_00126 (glnS); Cter: None |