HAMAP rule MF_00121

General rule information [?]

Accession	MF_00121
Dates	1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 28)

Name

GatB

Scope

Bacteria

Archaea

Templates

O30509 (GATB_BACSU); Q9LCX2 (GATB_THET8); O27341 (GATB_METTH): [Recover all]

case <OC:Bacteria> or <OC:Archaea>

Triggered by

end case

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

GATB

Protein name

RecName:		Full=Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B;
		Short=Asp/Glu-ADT subunit B;
		EC 6.3.5.-;

Gene name

gatB

Comments [?]

Function	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
Catalytic activity	RHEA:17521: ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate
	RHEA:14513: ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate
Subunit	Heterotrimer of A, B and C subunits.
Similarity	Belongs to the GatB/GatE family. GatB subfamily.

Keywords [?]

Gene Ontology [?]

GO:0050567; Molecular function: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity.
GO:0006412; Biological process: translation.

Cross-references [?]

Additional information [?]