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Annotation rule MF_00122
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General rule information [?]

Accession MF_00122
Dates 1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 26)
Name GatC
Scope
Bacteria
Archaea
Templates O06492 (GATC_BACSU); Q9LCX4 (GATC_THET8): [Recover all]
case <OC:Bacteria> or <OC:Archaea>
end case


Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
GATC
Protein name
RecName: Full=Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C;
Short=Asp/Glu-ADT subunit C;
EC 6.3.5.-;
Gene name
gatC

Comments [?]

Function Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
Catalytic activity RHEA:17521: ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate
RHEA:14513: ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate
Subunit Heterotrimer of A, B and C subunits.
Similarity Belongs to the GatC family.

Keywords [?]


Gene Ontology [?]

GO:0050567; Molecular function: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity.
GO:0006412; Biological process: translation.

Cross-references [?]

Pfam PF02686; Glu-tRNAGln; 1;
TIGRFAMs TIGR00135; GatC; 1;

Additional information [?]

Size range 89-104 amino acids
Related rules None
Fusion None
Comments Not a very convincing alignment. Divergent BORBU, METJA and TREPA not shown in alignment. Divergent METTH (still in TrEMBL). Divergent and fused sequences in MYCGE, MYCPN (still in TrEMBL).