HAMAP rule MF_00127
General rule information
[?]
Accession | MF_00127 |
Dates | 1-JUN-2001 (Created) 11-FEB-2022 (Last updated, Version 43) |
Name | His_tRNA_synth |
Scope | Bacteria
Archaea
Plastid |
Templates | P60906 (SYH_ECOLI); P60911 (SYH_STAAU); P56194 (SYH_THET8): [Recover all] |
case <OC:Bacteria> or <OC:Archaea> or <OG:Chloroplast>
Triggered by |
end case
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Identifier |
|
case <OC:Bacteria> or <OC:Archaea>
Protein name |
|
else case <OG:Chloroplast>
Protein name |
|
end case
Gene name |
|
Comments
[?]
Catalytic activity | RHEA:17313: ATP + L-histidine + tRNA(His) = AMP + diphosphate + H(+) + L-histidyl-tRNA(His)
EC 6.1.1.21 |
case <OC:Bacteria>
Subunit | Homodimer. |
end case
case not <OG:Chloroplast>
Subcellular location | Cytoplasm. |
end case
case <OG:Chloroplast>
Subcellular location | Plastid, chloroplast. |
end case
Similarity | Belongs to the class-II aminoacyl-tRNA synthetase family. |
Keywords
[?]
case not <OG:Chloroplast>
end case
Gene Ontology
[?]
GO:0005524; Molecular function: ATP binding.
GO:0004821; Molecular function: histidine-tRNA ligase activity.
GO:0006427; Biological process: histidyl-tRNA aminoacylation.
GO:0004821; Molecular function: histidine-tRNA ligase activity.
GO:0006427; Biological process: histidyl-tRNA aminoacylation.
case not <OG:Chloroplast>
GO:0005737; Cellular component: cytoplasm.
end case
case <OG:Chloroplast>
GO:0009507; Cellular component: chloroplast.
end case
Cross-references
[?]
Pfam | PF00587; tRNA-synt_2b; 1; |
PF03129; HGTP_anticodon; 1; | |
TIGRFAMs | TIGR00442; HisS; 1; |
PROSITE | PS50862; AA_TRNA_LIGASE_II; 1; |
Additional information
[?]
Size range | 403-523 amino acids |
Related rules | MF_00125 (HISZ) |
Fusion | None |
Comments | Divergent TROW8 and TROWT; not shown in alignment. It is difficult to distinguish between hisS and hisZ families. |