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Annotation rule MF_00127 |
General rule information
[?]
Accession |
MF_00127 |
Dates |
1-JUN-2001 (Created) 11-FEB-2022 (Last updated, Version 43) |
Scope |
Bacteria
Archaea
Plastid |
case <OC:Bacteria> or <OC:Archaea> or <OG:Chloroplast>
end case
Propagated annotation
[?]
Identifier, protein and gene names
[?]
case <OC:Bacteria> or <OC:Archaea>
Protein name |
RecName:
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Full=Histidine--tRNA ligase;
|
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EC 6.1.1.21;
|
AltName:
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Full=Histidyl-tRNA synthetase;
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Short=HisRS;
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else case <OG:Chloroplast>
Protein name |
RecName:
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Full=Histidine--tRNA ligase, chloroplastic;
|
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EC 6.1.1.21;
|
AltName:
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Full=Histidyl-tRNA synthetase;
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Short=HisRS;
|
|
end case
Catalytic activity |
RHEA:17313: ATP + L-histidine + tRNA(His) = AMP + diphosphate + H(+) + L-histidyl-tRNA(His)
EC 6.1.1.21
|
case <OC:Bacteria>
end case
case not <OG:Chloroplast>
Subcellular location |
Cytoplasm. |
end case
case <OG:Chloroplast>
Subcellular location |
Plastid, chloroplast. |
end case
Similarity |
Belongs to the class-II aminoacyl-tRNA synthetase family. |
case not <OG:Chloroplast>
end case
GO:0005524; Molecular function: ATP binding.
GO:0004821; Molecular function: histidine-tRNA ligase activity.
GO:0006427; Biological process: histidyl-tRNA aminoacylation.
case not <OG:Chloroplast>
end case
case <OG:Chloroplast>
end case
Additional information
[?]
Size range |
403-523 amino acids |
Related rules |
MF_00125 (HISZ) |
Fusion |
None |
Comments |
Divergent TROW8 and TROWT; not shown in alignment. It is difficult to distinguish between hisS and hisZ families. |