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Annotation rule MF_00129
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General rule information [?]

Accession MF_00129
Dates 1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 34)
Name MnmG_GidA
Templates P0A6U3 (MNMG_ECOLI); O66962 (MNMG_AQUAE); Q8KA85 (MNMG_CHLTE): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG;
AltName: Full=Glucose-inhibited division protein A;
Gene name
mnmG, gidA

Comments [?]

Function NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
Cofactor FAD
Subunit Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
Subcellular location Cytoplasm.
Similarity Belongs to the MnmG family.

Keywords [?]

Gene Ontology [?]

GO:0050660; Molecular function: flavin adenine dinucleotide binding.
GO:0008033; Biological process: tRNA processing.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF01134; GIDA; 1;
TIGRFAMs TIGR00136; GidA; 1;
PROSITE PS01280; GIDA_1; 1;
PS01281; GIDA_2; 1;

Features [?]

Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     13     18       FAD     G-[GATL]-G-H-[AS]-G  
NP_BIND     273     287       NAD     [GSA]-x-[RL]-[YH]-C-P-S-[IVFL]-[ED]-x-K-[VIFAL]-x-x-[FY]  
BINDING (Optional)     125     125       FAD; via amide nitrogen and carbonyl oxygen     [VI]   1
BINDING (Optional)     180     180       FAD     [ST]   1
BINDING (Optional)     370     370       FAD     [QN]   1

Additional information [?]

Size range 500-685 amino acids
Related rules None
Fusion None