HAMAP rule MF_00129
General rule information
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| Accession | MF_00129 |
| Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 37) |
| Name | MnmG_GidA |
| Scope(s) |
Bacteria |
| Template(s) | P0A6U3 (MNMG_ECOLI); O66962 (MNMG_AQUAE); Q8KA85 (MNMG_CHLTE); [ Recover all ] |
| Triggered by |
HAMAP; MF_00129 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | MNMG |
| Protein name | RecName: Full=tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG; AltName: Full=Glucose-inhibited division protein A; |
| Gene name | Name=mnmG; Synonyms=gidA; |
Comments
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| FUNCTION | NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. |
| COFACTOR | Name=FAD; Xref=ChEBI:CHEBI:57692; |
| SUBUNIT | Homodimer. Heterotetramer of two MnmE and two MnmG subunits. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the MnmG family. |
Keywords
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Gene Ontology
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| GO:0050660; Molecular function:flavin adenine dinucleotide binding |
| GO:0008033; Biological process:tRNA processing |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| Pfam | PF01134; GIDA; 1; |
| NCBIfam | TIGR00136; GidA; 1; |
| PROSITE | PS01280; GIDA_1; 1; |
| PROSITE | PS01281; GIDA_2; 1; |
Features
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| From: MNMG_ECOLI (P0A6U3) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 13 | 18 | /ligand="FAD" /ligand_id="ChEBI:CHEBI:57692" |
G-[GATL]-G-H-[AS]-G | ||||||||
| BINDING | 273 | 287 | /ligand="NAD(+)" /ligand_id="ChEBI:CHEBI:57540" |
[GSA]-x-[RL]-[YH]-C-P-S-[IVFL]-[ED]-x-K-[VIFAL]-x-x-[FY] | ||||||||
| BINDING | 125 | 125 | /ligand="FAD" /ligand_id="ChEBI:CHEBI:57692" |
[VI] | 1 | |||||||
| BINDING | 180 | 180 | /ligand="FAD" /ligand_id="ChEBI:CHEBI:57692" |
[ST] | 1 | |||||||
| BINDING | 370 | 370 | /ligand="FAD" /ligand_id="ChEBI:CHEBI:57692" |
[QN] | 1 | |||||||
Additional information
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| Size range | 500-685 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |