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Annotation rule MF_00131 |
General rule information
[?]
Accession |
MF_00131 |
Dates |
1-JUN-2001 (Created) 18-NOV-2019 (Last updated, Version 40) |
Scope |
Bacteria
Archaea
Plastid |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Protein name |
RecName:
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Full=Tryptophan synthase alpha chain;
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EC 4.2.1.20;
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Function |
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. |
Catalytic activity |
RHEA:10532: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan
EC 4.2.1.20
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Pathway |
Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5. |
Subunit |
Tetramer of two alpha and two beta chains. |
case <OG:Chloroplast>
Subcellular location |
Plastid, chloroplast. |
end case
Similarity |
Belongs to the TrpA family. |
GO:0004834; Molecular function: tryptophan synthase activity.
GO:0000162; Biological process: tryptophan biosynthetic process.
case <OG:Chloroplast>
end case
From: TRPA_ECOLI (P0A877) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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ACT_SITE
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49
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49
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Proton acceptor
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E
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ACT_SITE
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60
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60
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Proton acceptor
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[DE]
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Additional information
[?]
Size range |
239-293 amino acids |
Related rules |
None |
Fusion |
None |
Comments |
Highly divergent CHLTR; sequence not included in alignment |