HAMAP rule MF_00135
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_00135 |
| Accession | MF_00135 |
| Dates | 28-FEB-2005 (Created)
13-JAN-2025 (Last updated, Version 12) |
| Name | PRAI |
| Scope(s) |
Bacteria Archaea |
| Template(s) | Q56320; P00909; [ Recover all ] |
| Triggered by |
HAMAP; MF_00135 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | TRPF |
| Protein name | RecName: Full=N-(5'-phosphoribosyl)anthranilate isomerase; Short=PRAI; EC=5.3.1.24; |
| Gene name | Name=trpF; |
Comments
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| CATALYTIC ACTIVITY | Reaction=N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2- carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate; Xref=Rhea:RHEA:21540, ChEBI:CHEBI:18277, ChEBI:CHEBI:58613; EC=5.3.1.24; |
| PATHWAY | Amino-acid biosynthesis; L-tryptophan biosynthesis; L- tryptophan from chorismate: step 3/5. |
| SIMILARITY | Belongs to the TrpF family. |
Keywords
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Gene Ontology
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| GO:0004640; Molecular function:phosphoribosylanthranilate isomerase activity |
| GO:0000162; Biological process:L-tryptophan biosynthetic process |
Cross-references
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| Pfam | PF00697; PRAI; 1; |
Features
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Additional information
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| Size range | 195-241 amino acids |
| Related rules |
None |
| Fusion | Nter: MF_00134 (trpC) Cter: <Unknown> |
| Comments | Unknown C-terminal domain in LACLA (similar to BACSU YNAI); possible sequencing error |