HAMAP rule MF_00138
General rule information
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Accession | MF_00138 |
Dates | 1-JUN-2001 (Created) 23-MAR-2020 (Last updated, Version 31) |
Name | GARS |
Scope | Bacteria
Archaea |
Template | P15640 (PUR2_ECOLI) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Catalytic activity | RHEA:17453: 5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)-(5-phospho-beta-D-ribosyl)glycinamide + phosphate
EC 6.3.4.13 |
Pathway | Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2. |
case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
Subunit | Monomer. |
end case
Similarity | Belongs to the GARS family. |
Keywords
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Gene Ontology
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GO:0004637; Molecular function: phosphoribosylamine-glycine ligase activity.
GO:0006189; Biological process: 'de novo' IMP biosynthetic process.
GO:0006189; Biological process: 'de novo' IMP biosynthetic process.
Cross-references
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Pfam | PF01071; GARS_A; 1; |
PF02843; GARS_C; 1; | |
PF02844; GARS_N; 1; | |
TIGRFAMs | TIGR00877; PurD; 1; |
PROSITE | PS00184; GARS; 1; |
PS50975; ATP_GRASP; 1; trigger=PRU00409; |
Additional information
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Size range | 400-444 amino acids |
Related rules | None |
Fusion | None |
Comments | ARCFU is divergent, it has an insertion not found in other purD |