HAMAP rule MF_00138
General rule information
[?]
| Accession | MF_00138 |
| Dates | 1-JUN-2001 (Created) 23-MAR-2020 (Last updated, Version 31) |
| Name | GARS |
| Scope | Bacteria
Archaea |
| Template | P15640 (PUR2_ECOLI) |
| Triggered by |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
| Identifier |
|
| Protein name |
|
||||||||||||||||||||
| Gene name |
|
Comments
[?]
| Catalytic activity | RHEA:17453: 5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)-(5-phospho-beta-D-ribosyl)glycinamide + phosphate
EC 6.3.4.13 |
| Pathway | Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2. |
case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
| Subunit | Monomer. |
end case
| Similarity | Belongs to the GARS family. |
Keywords
[?]
Gene Ontology
[?]
GO:0004637; Molecular function: phosphoribosylamine-glycine ligase activity.
GO:0006189; Biological process: 'de novo' IMP biosynthetic process.
GO:0006189; Biological process: 'de novo' IMP biosynthetic process.
Cross-references
[?]
| Pfam | PF01071; GARS_A; 1; |
| PF02843; GARS_C; 1; | |
| PF02844; GARS_N; 1; | |
| TIGRFAMs | TIGR00877; PurD; 1; |
| PROSITE | PS00184; GARS; 1; |
| PS50975; ATP_GRASP; 1; trigger=PRU00409; |
Additional information
[?]
| Size range | 400-444 amino acids |
| Related rules | None |
| Fusion | None |
| Comments | ARCFU is divergent, it has an insertion not found in other purD |