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Annotation rule MF_00148
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General rule information [?]

Accession MF_00148
Dates 1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 30)
Name UDG
Scope
Bacteria
Template P12295 (UNG_ECOLI)
case <OC:Bacteria>
end case


Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
UNG
Protein name
RecName: Full=Uracil-DNA glycosylase;
Short=UDG;
EC 3.2.2.27;
Gene name
ung

Comments [?]

Function Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
Catalytic activity Reaction=Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.; EC=3.2.2.27;
Subcellular location Cytoplasm.
Similarity Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.

Keywords [?]


Gene Ontology [?]

GO:0004844; Molecular function: uracil DNA N-glycosylase activity.
GO:0006284; Biological process: base-excision repair.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF03167; UDG; 1;
TIGRFAMs TIGR00628; Ung; 1;
PROSITE PS00130; U_DNA_GLYCOSYLASE; 1;

Features [?]

From: UNG_ECOLI (P12295)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     64     64       Proton acceptor     D  

Additional information [?]

Size range 212-266 amino acids
Related rules None
Fusion None
Comments Probable wrong start in RALSO. Weird insert in CORGL; not shown in alignment.