 |
|
| Annotation rule MF_00148 |
General rule information
[?]
| Accession | MF_00148 |
| Dates | 1-JUN-2001 (Created) 18-NOV-2019 (Last updated, Version 30) |
| Name | UDG |
| Scope | Bacteria |
| Template | P12295 (UNG_ECOLI) |
case <OC:Bacteria>
| Triggered by |
end case
Propagated annotation
[?]
Identifier, protein and gene names
[?]
| Identifier |
|
| Protein name |
|
||||||||||||
| Gene name |
|
Comments
[?]
| Function | Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. |
| Catalytic activity | Reaction=Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.; EC=3.2.2.27; |
| Subcellular location | Cytoplasm. |
| Similarity | Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. |
Keywords
[?]
Gene Ontology
[?]
GO:0004844; Molecular function: uracil DNA N-glycosylase activity.
GO:0006284; Biological process: base-excision repair.
GO:0005737; Cellular component: cytoplasm.
GO:0006284; Biological process: base-excision repair.
GO:0005737; Cellular component: cytoplasm.
Cross-references
[?]
Features
[?]
| From: UNG_ECOLI (P12295) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 64 | 64 | Proton acceptor | D | ||||||||
Additional information
[?]
| Size range | 212-266 amino acids |
| Related rules | None |
| Fusion | None |
| Comments | Probable wrong start in RALSO. Weird insert in CORGL; not shown in alignment. |