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HAMAP rule MF_00149

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General rule information [?]

Accession MF_00149
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 19)
Name DNA_mis_repair
Scope(s) Bacteria
Template(s) P23367 (MUTL_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00149 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier MUTL
Protein name RecName: Full=DNA mismatch repair protein MutL;
Gene name Name=mutL;

Comments [?]

FUNCTIONThis protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
SIMILARITYBelongs to the DNA mismatch repair MutL/HexB family.

Keywords [?]

Gene Ontology [?]

GO:0006298; Biological process:mismatch repair

Cross-references [?]

Pfam PF01119; DNA_mis_repair; 1;
Pfam PF02518; HATPase_c; 1;
NCBIfam TIGR00585; Mutl; 1;

Features [?]

Additional information [?]

Size range 425-674 amino acids
Related rules None
Fusion Nter: None Cter: None

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