HAMAP rule MF_00149

General rule information [?]

Accession	MF_00149
Dates	1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 19)

Name	DNA_mis_repair

Scope

Bacteria

Archaea

Template

P23367 (MUTL_ECOLI)

Triggered by

HAMAP; MF_00149 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

MUTL

Protein name

RecName:

Full=DNA mismatch repair protein MutL;

Gene name

mutL

Comments [?]

Function	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
Similarity	Belongs to the DNA mismatch repair MutL/HexB family.

Keywords [?]

DNA damage
DNA repair

Gene Ontology [?]

GO:0006298; Biological process: mismatch repair.

Cross-references [?]

Pfam	PF01119; DNA_mis_repair; 1;
	PF02518; HATPase_c; 1;
NCBIfam	TIGR00585; Mutl; 1;
PROSITE	PS00058; DNA_MISMATCH_REPAIR_1; 1;

Additional information [?]

Size range	425-674 amino acids
Related rules	None
Fusion	None

View rule in raw text format (no links)