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HAMAP rule MF_00162

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General rule information [?]

Accession MF_00162
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 26)
Name GSH_S
Scope(s) Bacteria
Template(s) P04425 (GSHB_ECOLI); O32463 (GSHB_SYNE7); [ Recover all ]
Triggered by HAMAP; MF_00162 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier GSHB
Protein name RecName: Full=Glutathione synthetase;
AltName: Full=GSH synthetase;
AltName: Full=Glutathione synthase;
Gene name Name=gshB;

Comments [?]

CATALYTIC ACTIVITY Reaction=ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + glutathione + H(+) + phosphate; Xref=Rhea:RHEA:13557, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:57305, ChEBI:CHEBI:57925, ChEBI:CHEBI:58173, ChEBI:CHEBI:456216; EC=;
PATHWAYSulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.
SIMILARITYBelongs to the prokaryotic GSH synthase family.

Keywords [?]

Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0004363; Molecular function:glutathione synthase activity
GO:0006750; Biological process:glutathione biosynthetic process

Cross-references [?]

Pfam PF02955; GSH-S_ATP; 1;
Pfam PF02951; GSH-S_N; 1;
NCBIfam TIGR01380; glut_syn; 1;

Features [?]

Additional information [?]

Size range 307-324 amino acids
Related rules None
Fusion Nter: None Cter: None

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