HAMAP rule MF_00162

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_00162
Accession	MF_00162
Dates	28-FEB-2005 (Created) 02-SEP-2024 (Last updated, Version 19)
Name	GSH_S
Scope(s)	Bacteria
Template(s)	P04425; O32463; [ Recover all ]
Triggered by	HAMAP; MF_00162 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	GSHB
Protein name	RecName: Full=Glutathione synthetase; EC=6.3.2.3; AltName: Full=GSH synthetase; Short=GSH-S; Short=GSHase; AltName: Full=Glutathione synthase;
Gene name	Name=gshB;

Comments [?]

CATALYTIC ACTIVITY	Reaction=gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+); Xref=Rhea:RHEA:13557, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:57305, ChEBI:CHEBI:57925, ChEBI:CHEBI:58173, ChEBI:CHEBI:456216; EC=6.3.2.3;
PATHWAY	Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.
SIMILARITY	Belongs to the prokaryotic GSH synthase family.

Keywords [?]

Gene Ontology [?]

GO:0005524; Molecular function:ATP binding

GO:0004363; Molecular function:glutathione synthase activity

GO:0006750; Biological process:glutathione biosynthetic process

Cross-references [?]

Features [?]

Additional information [?]