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HAMAP rule MF_00199

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General rule information [?]

Accession MF_00199
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 26)
Name ApaH
Scope(s) Bacteria
Template(s) P05637 (APAH_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00199 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier APAH
Protein name RecName: Full=Bis(5'-nucleosyl)-tetraphosphatase, symmetrical;
                 EC=3.6.1.41;
AltName: Full=Ap4A hydrolase;
AltName: Full=Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase;
AltName: Full=Diadenosine tetraphosphatase;
Gene name Name=apaH;

Comments [?]

FUNCTIONHydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
CATALYTIC ACTIVITY Reaction=H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate = 2 ADP + 2 H(+); Xref=Rhea:RHEA:24252, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:58141, ChEBI:CHEBI:456216; EC=3.6.1.41;
SIMILARITYBelongs to the Ap4A hydrolase family.

Keywords [?]


Gene Ontology [?]

GO:0008803; Molecular function:bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity

Cross-references [?]

Pfam PF00149; Metallophos; 1;
NCBIfam TIGR00668; ApaH; 1;

Features [?]


Additional information [?]

Size range 268-324 amino acids
Related rules None
Fusion Nter: None Cter: None



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