HAMAP rule MF_00203
General rule information
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Accession | MF_00203 |
Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 29) |
Name | UvrC |
Scope(s) |
Bacteria Archaea |
Template(s) | P0A8G0 (UVRC_ECOLI); [ Recover all ] |
Triggered by |
HAMAP; MF_00203 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | UVRC |
Protein name | RecName: Full=UvrABC system protein C; Short=Protein UvrC; AltName: Full=Excinuclease ABC subunit C; |
Gene name | Name=uvrC; |
Comments
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FUNCTION | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. |
SUBUNIT | Interacts with UvrB in an incision complex. |
SUBCELLULAR LOCATION | Cytoplasm. |
SIMILARITY | Belongs to the UvrC family. |
Keywords
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Gene Ontology
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GO:0003677; Molecular function:DNA binding |
GO:0009381; Molecular function:excinuclease ABC activity |
GO:0006281; Biological process:DNA repair |
GO:0006289; Biological process:nucleotide-excision repair |
GO:0009432; Biological process:SOS response |
GO:0005737; Cellular component:cytoplasm |
Cross-references
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Pfam | PF01541; GIY-YIG; 1; |
Pfam | PF02151; UVR; 1; |
Pfam | PF08459; UvrC_HhH_N; 1; |
NCBIfam | TIGR00194; UvrC; 1; |
PROSITE | PS50164; GIY_YIG; 1; |
PROSITE | PS50151; UVR; 0-1; |
PROSITE | PS50165; UVRC; 1; |
Features
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Additional information
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Size range | 519-747 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |
Comments | Weird insertions in STRCO and TREPA |