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Annotation rule MF_00203
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General rule information [?]

Accession MF_00203
Dates 1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 28)
Name UvrC
Scope
Bacteria
Archaea
Template P0A8G0 (UVRC_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
UVRC
Protein name
RecName: Full=UvrABC system protein C;
Short=Protein UvrC;
AltName: Full=Excinuclease ABC subunit C;
Gene name
uvrC

Comments [?]

Function The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
Subunit Interacts with UvrB in an incision complex.
Subcellular location Cytoplasm.
Similarity Belongs to the UvrC family.

Keywords [?]

Cytoplasm
DNA damage
SOS response
Excision nuclease
DNA repair
DNA excision

Gene Ontology [?]

GO:0003677; Molecular function: DNA binding.
GO:0009381; Molecular function: excinuclease ABC activity.
GO:0006281; Biological process: DNA repair.
GO:0006289; Biological process: nucleotide-excision repair.
GO:0009432; Biological process: SOS response.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF01541; GIY-YIG; 1;
PF02151; UVR; 1;
PF08459; UvrC_HhH_N; 1;
TIGRFAMs TIGR00194; UvrC; 1;
PROSITE PS50164; GIY_YIG; 1; trigger=PRU00977;
PS50151; UVR; 0-1; trigger=PRU00217;
PS50165; UVRC; 1;

Additional information [?]

Size range 519-747 amino acids
Related rules None
Fusion None
Comments Weird insertions in STRCO and TREPA


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