HAMAP rule MF_00203
General rule information
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Accession | MF_00203 |
Dates | 1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 29) |
Name | UvrC |
Scope | Bacteria
Archaea |
Template | P0A8G0 (UVRC_ECOLI) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. |
Subunit | Interacts with UvrB in an incision complex. |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the UvrC family. |
Keywords
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Gene Ontology
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GO:0003677; Molecular function: DNA binding.
GO:0009381; Molecular function: excinuclease ABC activity.
GO:0006281; Biological process: DNA repair.
GO:0006289; Biological process: nucleotide-excision repair.
GO:0009432; Biological process: SOS response.
GO:0005737; Cellular component: cytoplasm.
GO:0009381; Molecular function: excinuclease ABC activity.
GO:0006281; Biological process: DNA repair.
GO:0006289; Biological process: nucleotide-excision repair.
GO:0009432; Biological process: SOS response.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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Pfam | PF01541; GIY-YIG; 1; |
PF02151; UVR; 1; | |
PF08459; UvrC_HhH_N; 1; | |
NCBIfam | TIGR00194; UvrC; 1; |
PROSITE | PS50164; GIY_YIG; 1; trigger=PRU00977; |
PS50151; UVR; 0-1; trigger=PRU00217; | |
PS50165; UVRC; 1; |
Additional information
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Size range | 519-747 amino acids |
Related rules | None |
Fusion | None |
Comments | Weird insertions in STRCO and TREPA |