HAMAP rule MF_00203

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_00203
Accession	MF_00203
Dates	28-FEB-2005 (Created) 01-JUN-2023 (Last updated, Version 20)
Name	UvrC
Scope(s)	Bacteria Archaea
Template(s)	P0A8G0; [ Recover all ]
Triggered by	HAMAP; MF_00203 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	UVRC
Protein name	RecName: Full=UvrABC system protein C; Short=Protein UvrC; AltName: Full=Excinuclease ABC subunit C;
Gene name	Name=uvrC;

Comments [?]

FUNCTION	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
SUBUNIT	Interacts with UvrB in an incision complex.
SUBCELLULAR LOCATION	Cytoplasm.
SIMILARITY	Belongs to the UvrC family.

Keywords [?]

Gene Ontology [?]

GO:0003677; Molecular function:DNA binding

GO:0009381; Molecular function:excinuclease ABC activity

GO:0006281; Biological process:DNA repair

GO:0006289; Biological process:nucleotide-excision repair

GO:0009432; Biological process:SOS response

GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Features [?]

Additional information [?]

Size range	519-747 amino acids
Related rules	None
Fusion	Nter: None Cter: None
Comments	Weird insertions in STRCO and TREPA