HAMAP rule MF_00215

General rule information [?]

Accession	MF_00215
Dates	1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 33)

Name	Pantothen_kinase_1

Scope

Bacteria

Template

P0A6I3 (COAA_ECOLI)

Triggered by

HAMAP; MF_00215 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

COAA

Protein name

RecName:		Full=Pantothenate kinase;
		EC 2.7.1.33;
AltName:		Full=Pantothenic acid kinase;

Gene name

coaA

Comments [?]

Catalytic activity	RHEA:16373: (R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+) EC 2.7.1.33
Pathway	Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.
Subcellular location	Cytoplasm.
Similarity	Belongs to the prokaryotic pantothenate kinase family.

Keywords [?]

Cytoplasm
Transferase
Kinase
ATP-binding
Nucleotide-binding
Coenzyme A biosynthesis

Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0004594; Molecular function: pantothenate kinase activity.
GO:0015937; Biological process: coenzyme A biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam	PF00485; PRK; 1;
NCBIfam	TIGR00554; PanK_bact; 1;

Features [?]

From: COAA_ECOLI (P0A6I3)

Key From To Description Tag Condition FTGroup

BINDING 95 102 /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 G-S-V-[ASG]-V-G-K-[ST]

Additional information [?]

Size range	306-331 amino acids
Related rules	None
Fusion	None
Comments	Possible wrong start in RHIME, STRCO

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