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HAMAP rule MF_00215

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General rule information [?]

Accession MF_00215
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 33)
Name Pantothen_kinase_1
Scope(s) Bacteria
Template(s) P0A6I3 (COAA_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00215 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier COAA
Protein name RecName: Full=Pantothenate kinase;
                 EC=2.7.1.33;
AltName: Full=Pantothenic acid kinase;
Gene name Name=coaA;

Comments [?]

CATALYTIC ACTIVITY Reaction=(R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+); Xref=Rhea:RHEA:16373, ChEBI:CHEBI:10986, ChEBI:CHEBI:15378, ChEBI:CHEBI:29032, ChEBI:CHEBI:30616, ChEBI:CHEBI:456216; EC=2.7.1.33;
PATHWAYCofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)- pantothenate: step 1/5.
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the prokaryotic pantothenate kinase family.

Keywords [?]


Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0004594; Molecular function:pantothenate kinase activity
GO:0015937; Biological process:coenzyme A biosynthetic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF00485; PRK; 1;
NCBIfam TIGR00554; PanK_bact; 1;

Features [?]

From: COAA_ECOLI (P0A6I3)
Key From To Description Tag Condition FTGroup
BINDING 95 102 /ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"
G-S-V-[ASG]-V-G-K-[ST]

Additional information [?]

Size range 306-331 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments Possible wrong start in RHIME, STRCO



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