HAMAP rule MF_00215
General rule information
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| Accession | MF_00215 |
| Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 33) |
| Name | Pantothen_kinase_1 |
| Scope(s) |
Bacteria |
| Template(s) | P0A6I3 (COAA_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_00215 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | COAA |
| Protein name | RecName: Full=Pantothenate kinase; EC=2.7.1.33; AltName: Full=Pantothenic acid kinase; |
| Gene name | Name=coaA; |
Comments
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| CATALYTIC ACTIVITY | Reaction=(R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+); Xref=Rhea:RHEA:16373, ChEBI:CHEBI:10986, ChEBI:CHEBI:15378, ChEBI:CHEBI:29032, ChEBI:CHEBI:30616, ChEBI:CHEBI:456216; EC=2.7.1.33; |
| PATHWAY | Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)- pantothenate: step 1/5. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the prokaryotic pantothenate kinase family. |
Keywords
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Gene Ontology
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| GO:0005524; Molecular function:ATP binding |
| GO:0004594; Molecular function:pantothenate kinase activity |
| GO:0015937; Biological process:coenzyme A biosynthetic process |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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Features
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| From: COAA_ECOLI (P0A6I3) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 95 | 102 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" |
G-S-V-[ASG]-V-G-K-[ST] | ||||||||
Additional information
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| Size range | 306-331 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | Possible wrong start in RHIME, STRCO |