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Annotation rule MF_00221
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General rule information [?]

Accession MF_00221
Dates 1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 40)
Name NRAMP
Scope
Bacteria
Templates P96593 (MNTH_BACSU); P0A769 (MNTH_ECOLI); P9WIZ5 (MNTH_MYCTU): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
MNTH
Protein name
RecName: Full=Divalent metal cation transporter MntH;
Gene name
mntH

Comments [?]

Function H(+)-stimulated, divalent metal cation uptake system.
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location Cell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
Subcellular location Cell inner membrane; Multi-pass membrane protein.
end case
Similarity Belongs to the NRAMP family.

Keywords [?]

case defined <Property:Membrane> and <Property:Membrane=2>
end case

Gene Ontology [?]

GO:0046872; Molecular function: metal ion binding.
GO:0015293; Molecular function: symporter activity.
GO:0030001; Biological process: metal ion transport.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

Pfam PF01566; Nramp; 1;
PRINTS PR00447; NATRESASSCMP; 1;
TIGRFAMs TIGR01197; Nramp; 1;

Computed features [?]

case not <OC:Escherichia> and not <OC:Shigella> and not <OC:Salmonella>
General Transmembrane; -; 9-11; trigger=yes;
end case

Features [?]

case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
From: MNTH_ECOLI (P0A769)
Key     From     To       Description   Tag   Condition   FTGroup
TOPO_DOM     Nter     19       Cytoplasmic        
TRANSMEM     20     39       Helical        
TOPO_DOM     40     51       Periplasmic        
TRANSMEM     52     71       Helical        
TOPO_DOM     72     95       Cytoplasmic        
TRANSMEM     96     118       Helical        
TOPO_DOM     119     125       Periplasmic        
TRANSMEM     126     145       Helical        
TOPO_DOM     146     155       Cytoplasmic        
TRANSMEM     156     175       Helical        
TOPO_DOM     176     196       Periplasmic        
TRANSMEM     197     220       Helical        
TOPO_DOM     221     238       Cytoplasmic        
TRANSMEM     239     258       Helical        
TOPO_DOM     259     276       Periplasmic        
TRANSMEM     277     297       Helical        
TOPO_DOM     298     327       Cytoplasmic        
TRANSMEM     328     344       Helical        
TOPO_DOM     345     350       Periplasmic        
TRANSMEM     351     370       Helical        
TOPO_DOM     371     387       Cytoplasmic        
TRANSMEM     388     406       Helical        
TOPO_DOM     407     Cter       Periplasmic        
end case

Additional information [?]

Size range 409-472 amino acids
Related rules None
Fusion None
Comments Possible wrong start in some sequences.