HAMAP rule MF_00221
General rule information
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| Accession | MF_00221 |
| Dates | 1-JUN-2001 (Created)
28-NOV-2023 (Last updated, Version 42) |
| Name | NRAMP |
| Scope(s) |
Bacteria |
| Template(s) | P96593 (MNTH_BACSU); P0A769 (MNTH_ECOLI); P9WIZ5 (MNTH_MYCTU); [ Recover all ] |
| Triggered by |
HAMAP; MF_00221 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | MNTH |
| Protein name | RecName: Full=Divalent metal cation transporter MntH; |
| Gene name | Name=mntH; |
Comments
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| FUNCTION | H(+)-stimulated, divalent metal cation uptake system. |
| case not defined <Property:Membrane> or <Property:Membrane=1> | |
| SUBCELLULAR LOCATION | Cell membrane; Multi-pass membrane protein. |
| else case <Property:Membrane=2> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Multi-pass membrane protein. |
| end case | |
| SIMILARITY | Belongs to the NRAMP family. |
Keywords
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| case defined <Property:Membrane> and <Property:Membrane=2> | |
| Cell inner membrane | |
| end case | |
| Cell membrane | |
| Ion transport | |
| Membrane | |
| Symport | |
| Transmembrane | |
| Transmembrane helix | |
| Transport | |
Gene Ontology
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| GO:0046872; Molecular function:metal ion binding |
| GO:0015293; Molecular function:symporter activity |
| GO:0030001; Biological process:metal ion transport |
| GO:0005886; Cellular component:plasma membrane |
Cross-references
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| Pfam | PF01566; Nramp; 1; |
| PRINTS | PR00447; NATRESASSCMP; 1; |
| NCBIfam | TIGR01197; Nramp; 1; |
| General | Transmembrane; -; 9-11; |
Features
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| From: MNTH_ECOLI (P0A769) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella> | ||||||||||||
| TOPO_DOM | Nter | 19 | /note="Cytoplasmic" | |||||||||
| TRANSMEM | 20 | 39 | /note="Helical" | |||||||||
| TOPO_DOM | 40 | 51 | /note="Periplasmic" | |||||||||
| TRANSMEM | 52 | 71 | /note="Helical" | |||||||||
| TOPO_DOM | 72 | 95 | /note="Cytoplasmic" | |||||||||
| TRANSMEM | 96 | 118 | /note="Helical" | |||||||||
| TOPO_DOM | 119 | 125 | /note="Periplasmic" | |||||||||
| TRANSMEM | 126 | 145 | /note="Helical" | |||||||||
| TOPO_DOM | 146 | 155 | /note="Cytoplasmic" | |||||||||
| TRANSMEM | 156 | 175 | /note="Helical" | |||||||||
| TOPO_DOM | 176 | 196 | /note="Periplasmic" | |||||||||
| TRANSMEM | 197 | 220 | /note="Helical" | |||||||||
| TOPO_DOM | 221 | 238 | /note="Cytoplasmic" | |||||||||
| TRANSMEM | 239 | 258 | /note="Helical" | |||||||||
| TOPO_DOM | 259 | 276 | /note="Periplasmic" | |||||||||
| TRANSMEM | 277 | 297 | /note="Helical" | |||||||||
| TOPO_DOM | 298 | 327 | /note="Cytoplasmic" | |||||||||
| TRANSMEM | 328 | 344 | /note="Helical" | |||||||||
| TOPO_DOM | 345 | 350 | /note="Periplasmic" | |||||||||
| TRANSMEM | 351 | 370 | /note="Helical" | |||||||||
| TOPO_DOM | 371 | 387 | /note="Cytoplasmic" | |||||||||
| TRANSMEM | 388 | 406 | /note="Helical" | |||||||||
| TOPO_DOM | 407 | Cter | /note="Periplasmic" | |||||||||
| end case | ||||||||||||
Additional information
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| Size range | 409-472 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | Possible wrong start in some sequences. |